Alkyl(aryl)iodonium Reagents for Late-Stage Alkylation

用于后期烷基化的烷基（芳基）碘鎓试剂

• 批准号: EP/W00934X/1
• 负责人: Miriam L. O'Duill
• 金额: $ 53.9万
• 依托单位: University of Nottingham
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FW00934X%2F1
• 关键词: Alkyl; aryl; iodonium; Reagents; Late

Creating new molecules is of crucial importance in the development of pharmaceuticals, pesticides, perfumes and materials. Despite decades of research, however, some structural motifs are still very difficult or even impossible to create with the tools we currently have at our disposal. In this project, we will develop new reagents and reactions that will allow access to some of these more complicated molecules with the aim of aiding pharmaceutical companies in the development of new drugs and medical imaging probes.

创建新分子对于制药，农药，香水和材料的开发至关重要。但是，尽管进行了数十年的研究，但某些结构图案仍然非常困难甚至无法创建我们目前可以使用的工具。在该项目中，我们将开发新的试剂和反应，以允许使用这些更复杂的分子，以帮助制药公司开发新药和医学成像探针。