How does neurogenesis in the adult hippocampus influence learning & memory?

成人海马体的神经发生如何影响学习

• 批准号: DE150101578
• 负责人: A/Prof Jana Vukovic
• 金额: $ 27.39万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2018-07-27
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE150101578
• 关键词: How; does; neurogenesis; adult; hippocampus

One of the primary brain structures critical for learning and memory in animals and humans is the hippocampus, where regulated production of new neurons throughout life (i.e. adult neurogenesis) underpins these cognitive functions. The project aims to unravel how adult-born neurons exert their influence over behaviour by determining when newly born neurons become critical for behaviour and the connections made by these cells within the hippocampal network. It aims to provide fundamental new insight into the stages at which these neurons are important for the acquisition of spatial task versus the recall of spatial tasks.

海马体是对动物和人类学习和记忆至关重要的主要大脑结构之一，在整个生命过程中，新神经元的调节产生（即成人神经发生）支撑着这些认知功能。该项目旨在通过确定新生神经元何时对行为变得至关重要以及这些细胞在海马网络内建立的连接来揭示成年神经元如何对行为产生影响。它的目的是为这些神经元对于空间任务的获取和空间任务的回忆的重要阶段提供基本的新见解。