PROCUREMENT OF PRIMARY REFERENCE MATERIALS

主要参考材料的采购

• 批准号: 3661405
• 负责人: KATHLEEN A WHITE
• 金额: $ 4.92万
• 依托单位: MERCOR, INC.
• 依托单位国家: 美国
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-06-30 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3661405
• 关键词: bioengineering /biomedical engineering; biomaterial development /preparation; polyurethanes; surface property

The proposed work involves the synthesis of a lot of additive-free polytetramethylene (PTMO), 4, 4 diphenylmethane diisothionate (MDI), and polyurethaneurea (PUU). They will study bulk and surface characterization, and fabrication into tubes and sheets. Pilot quantity material goals have been identified. Fabrication details are provided. Sterile, packaged samples of the polyurethaneurea will be characterized to determine the effect of gamma radiation and to assess time dependent surface changes in the polyurethaneurea primary reference materials. These studies are aimed at determining the effect of degradation by the gamma irradiation sterilization technique. In addition, the investigators will also address time-dependent changes that might occur during storage prior to application.

本文的工作涉及到合成大量的无添加剂的 聚四亚甲基（PTMO）、4，4-二苯基甲烷二异硫代磺酸酯（MDI），和 聚脲（PUU）。 他们将研究体积和表面特性， 并加工成管和板。 试点数量材料目标有 被识别。 提供了制造细节。 无菌包装 将对聚脲样品进行表征，以确定 伽马辐射的影响，并评估 聚氨酯脲一级参考物质。 这些研究旨在 在确定伽马辐照降解的影响时， 灭菌技术 此外，调查人员还将讨论 在应用之前的存储期间可能发生的时间依赖性变化。