MEDICAL MYCOLOGY

这是一个医学真菌学的项目。每个研究项目都包含 与医学真菌学的一个重要领域有关， 由该领域的一位专家指导。尽管该计划分为 独立的项目，它们是相互关联的，并因这种互动而得到加强。 实际上，这是一种协调一致的方法，以实现改善 全身性真菌感染的结局。 该计划的项目包括以下几个方面：1.分子生物学 二相性致病真菌组织胞浆的生长和相变 胶囊。2.开发新的灵敏和特异的诊断方法 这将使对系统性真菌感染的早期诊断成为可能。3.主持人 涉及体液免疫和细胞免疫作用的真菌相互作用 对病原真菌的反应。4.开发新形式的化疗和 更有效地使用较老的代理。5.协调努力，使用 该计划的参与者教授现代医学真菌学方法。

This is a program in medical mycology. Each of the research projects contained in the program is concerned with an important area of medical mycology and is directed by an expert in that area. Although the program is divided into separate projects, they are interrelated and strengthened by this interaction. In effect, this is a coordinated approach to the objective of improving the outcome of systemic fungal infections. The projects in the program involve the following: 1. The molecular biology of growth and phase transition of the dimorphic pathogenic fungus Histoplasma capsulatum. 2. Development of new sensitive and specific diagnostic methods which will allow earlier diagnosis of systemic fungal infections. 3. Host fungal interactions which involve the role of humoral and cell mediated immune responses to pathogenic fungi. 4. Development of new forms of chemotherapy and more efficient use of the older agents. 5. A coordinated effort using the participants in the program to teach a modern approach to medical mycology.