STUDY TO DETERMINE WHETHER CARDIOPULMONARY BYPASS INDUCES AN ANTIBODY RESPONSE

研究确定体外循环是否引起抗体反应

• 批准号: 3740750
• 负责人: ROBERT E SHADDY
• 金额: --
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3740750
• 关键词: antibody; heart /lung bypass; homologous transplantation; human subject; transplant rejection; transplantation immunology

This study will determine if allograft implantation induces an antibody response in the recipient manifested as an elevated Panel Reactive Antibody (PRA) in the recipient. Also to be determined is whether or not there is any correlation between the degree of antibody response in the recipient and subsequent graft dysfunction.

这项研究将确定同种异体移植物植入是否会诱导抗体 接收者的反应表现为面板反应性升高 受体体内有抗体 (PRA)。 还有待确定的是是否 抗体反应程度之间存在相关性 受体和随后的移植物功能障碍。