MENSTRUAL CYCLE INFLUENCE ON ALPRAZOLAM PHARMACODYNAMICS

月经周期对阿普唑仑药效的影响

• 批准号: 3739073
• 负责人: JAMES W MCAULEY
• 金额: --
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3739073
• 关键词: alprazolam; benzodiazepines; female; human subject; menstrual cycle; pharmacokinetics; progesterone; women's health

The objective of this study is to determine whether benzodiazepine sensitivity is influenced by endogenous progesterone levels during the menstrual cycle in fourteen normally-menstruating women. If women respond differently to the administration of a drug during their menstrual cycle, they may expect a certain response but actually receive a very different effect.

本研究的目的是确定苯二氮卓类药物是否