HIGH VS LOW DOSE OF D-PENICILLAMINE IN EARLY SYSTEMIC SCLEROSIS

早期系统性硬化症中高剂量与低剂量 D-青霉胺的比较

• 批准号: 3740147
• 负责人: DAVID HARRIS COLLIER
• 金额: --
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3740147
• 关键词: clinical trials; connective tissue disorder chemotherapy; drug administration rate /duration; human subject; human therapy evaluation; penicillamine; skin disorder; skin disorder chemotherapy

This is a multicenter, double blind,placebo controlled study to determine the effect of low dose (125 mg every other day) vs high dose (1000 mg per day) of d-penicillamine on patients with generalized (diffuse) systemic sclerosis of less than 18 months duration.

这是一项多中心、双盲、安慰剂对照研究 确定低剂量（每隔一天 125 毫克）与高剂量的效果 （每天 1000 毫克）d-青霉胺治疗全身性 持续时间少于 18 个月的（弥漫性）系统性硬化症。