BONE DENSITY IN HYPERPARATHYROIDISM

甲状旁腺功能亢进症的骨密度

• 批准号: 3744426
• 负责人: GHADA EH FULEIHAN
• 金额: --
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3744426
• 关键词: biochemistry; bone density; bone metabolism disorder; hormone regulation /control mechanism; human subject; hyperparathyroidism; longitudinal human study; medical complication; minerals; parathyroid hormones; parathyroidectomy; pathologic bone resorption; pathologic process; postoperative state

This is a non-randomized, prospective study to evaluate the progression of bone loss in patients with primary hyperparathyroidism. The hypotheses to be tested are: 1)Bone loss in untreated patients is progressive over time; 2)Treatment of patients with parathyroid surgery may result in an increase in bone mineral content; 3)Biochemical indices of bone turnover and calciotropic hormones may predict the patients to benefit most from surgery.

这是一项非随机、前瞻性研究，旨在评估 原发性甲状旁腺功能亢进患者的骨质流失。 的 有待检验的假设是：1）未经治疗的患者的骨丢失是 随时间进展; 2）甲状旁腺手术患者的治疗 可能导致骨矿物质含量增加; 3）生化指标 骨转换和促钙激素可能预测患者 手术受益最多