Convergent regulation of sympathetic neuronal excitability by peptide hormones and transmitters

肽激素和递质对交感神经元兴奋性的聚合调节

• 批准号: nhmrc : 535081
• 负责人: Prof Ian Gibbins
• 金额: $ 33.24万
• 依托单位: Flinders University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/convergent-regulation-sympathetic-hormones-transmitters/96743
• 关键词: Convergent; regulation; sympathetic; neuronal; excitability

This project will examine how hormones involved in regulating blood pressure interact with the nerves that control blood flow to the gut. We will combine electrical recordings of the activity of single nerve cells with an innovative new method of optically tracking the movements of single molecules, including hormons and neuronal messengers, that send signals to the nerve cells. Our results will reveal how blood pressure is normally maintained at healthy levels, even if we are ill.

这个项目将研究参与调节血压的激素如何与控制流向肠道的血液的神经相互作用。我们将把对单个神经细胞活动的电子记录与一种创新的新方法结合起来，这种方法可以光学跟踪向神经细胞发送信号的单分子的运动，包括激素和神经元信使。我们的结果将揭示，即使我们生病了，血压是如何正常保持在健康水平的。