ACQUISITION OF T3D FOR BIOLOGICAL RESEARCH

匹兹堡超级计算中心(PSC)将其部分 Cray Research的新大规模并行处理器T3D，在计算上 要求苛刻的、前沿的结构生物学和 目前由美国国立卫生研究院资助的自动化光学显微镜。 T3D将通过领先的方式实现非常重要的生物学研究 结构生物学研究人员(布鲁克斯、科尔曼、布伦格)。此外 使这些研究人员在蛋白质方面取得实质性进展 折叠、结晶提纯和了解酶 反应，这项研究将推进这种广泛的适用性 使用了CHARMM、AMBER和X-PLOR等包，然后可以利用这些包 整个科学界。T3D还将实现显著的 自动交互显微镜的研究进展 (Taylor)，这将显著提高我们对细胞 流程。 新的T3D将得到匹兹堡超级计算的全面支持 中心，在支持前沿方面具有长期经验 计算引擎，具有强大的操作和用户支持。T3D 将完全集成到PSC的领先高性能中 具有最先进的文件系统、数据存储、 可视化和联网能力。

The Pittsburgh Supercomputing Center (PSC) is devoting portions of its T3D, Cray Research's new massively parallel processor, to computationally demanding, leading-edge research projects in structural biology and in automated light microscopy which are currently funded by NIH. The T3D will enable very significant biological research by leading researchers in structural biology (Brooks, Kollman, Brunger). Besides allowing these researchers to make substantial progress in protein folding, crystallographic refinement, and understanding enzymatic reactions, this research will advance the applicability of such widely used packages as CHARMM, AMBER and X-PLOR, which can then be exploited by the entire scientific community. The T3D will also enable significant advances in the development of an automated interactive microscope (Taylor), which will markedly improve our understanding of cellular processes. The new T3D will be fully supported by the Pittsburgh Supercomputing Center, which has long experience in supporting leading-edge computational engines, with robust operations and user support. The T3D will be fully integrated into PSC's leading-edge high performance computing environment, with state-of-the-art file systems, data storage, visualization and networking capability.