Critical Infection: Ecological Solutions to Antibiotic Resistance

申请者将把新型微生物数据和诊断工具应用于危重病人的早期干预，并直接测试它们对临床结果的影响。他还将引入新的疗法，以恢复肠道细菌对抗生素的敏感性，并在新资助的项目拨款中检查抗生素对危重病人的临床和微生物学影响。重叠的研究主题都与他的临床和专业角色直接相关。

The applicant will apply new types of microbial data and diagnostic tools to early interventions in the critically ill and directly test their impact on clinical outcomes. He will also introduce novel therapies to restore antibiotic susceptibility to enteric bacteria and examine the clinical and microbiological effects of antibiotic decontamination of the critically ill in newly funded project grants. Overlapping research themes all link directly to his clinical and professional roles.