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CHRONOENDOCRINOLOGY OF SLEEP DISTURBANCES IN DEPRESSION

CHRONOENDOCRINOLOGY OF SLEEP DISTURBANCES IN DEPRESSION
抑郁症睡眠障碍的时间内分泌学
批准号：
3786679
负责人：
RUSSELL E POLAND
金额：
$0.0万
依托单位：
LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3786679
关键词：
REM sleep adrenocorticotropic hormone anticholinergic agent bioperiodicity clinical depression corticotropin releasing factor dexamethasone suppression test electroencephalography hormone regulation /control mechanism human subject human therapy evaluation pituitary adrenal axis serotonin inhibitor sleep disorders

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中文摘要
翻译
中枢神经系统-垂体-肾上腺功能异常关系的研究 抑郁症患者睡眠脑电轴向调节与REM潜伏期缩短 受试者和正常对照组使用ACTH或CRF刺激和 地塞米松抑制试验。来检验胆碱能 而5-羟色胺能拮抗剂对这些测试的影响较小 情绪低落。
英文摘要
To study the relationship among abnormalities in CNS-pituitary-adrenal axis regulation and reduced REM latency shown on sleep EEG in depressed subjects and normal controls using ACTH or CRF stimulation and dexamethasone suppression tests. To test the hypothesis that cholinergic and serotonergic antagonists have less effect on these tests in the depressed.
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会议论文
CIRCADIAN VARIATION OF DEXAMETHASONE PHARMACOKINETICS AND CORTISOL SUPPRESSION
CHRONOENDOCRINOLOGY OF SLEEP DISTURBANCES IN DEPRESSION
CHRONOENDOCRINOLOGY OF SLEEP DISTURBANCES IN DEPRESSION
PSYCHIATRIC DIAGNOSIS AND BIOLOGICAL MARKERS IN PATIENT WITH NEURASTHENIA
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