ACETYLCHOLINE IN HEART TRANSPLANT AND AUTONOMIC FAILURE

乙酰胆碱在心脏移植和自主神经衰竭中的作用

• 批准号: 3785717
• 负责人: DAVID M ROBERTSON
• 金额: --
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3785717
• 关键词: acetylcholine; autonomic disorder; congenital heart disorder; denervation; heart conduction system; heart disorder chemotherapy; heart pharmacology; heart rate; heart transplantation; human subject; human therapy evaluation

To assess the effects of acetylcholine on heart rate and atrioventricular conduction in patients with cardiac denervation. To compare possible parasympathetic denervation hypersensitivity (as tested by acetylcholine) in patients with cardiac transplantation and those with autonomic failure (Shy-Drager or Bradbury-Eggleston Syndrome).

目的探讨乙酰胆碱对心率及房室电位的影响