INTESTINAL RESISTANCE TO ENDOGENOUS 1,25-DIHYDROXYVITAMIN D3 WITH AGING

随着年龄的增长，肠道对内源性 1,25-二羟基维生素 D3 的抵抗力

• 批准号: 3786875
• 负责人: M F BURRITT
• 金额: --
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3786875
• 关键词: 1,25 dihydroxycholecalciferol; age difference; aging; dietary calcium; female; gastrointestinal disorder; gastrointestinal disorder diagnosis; gastrointestinal nutrient absorption; hormone regulation /control mechanism; human old age (65+); human subject; nutrition of aging; nutrition related tag; young adult human (21-34)

To test the hypothesis that there is an intrinsic gut defect by determining whether the intestinal responsiveness to increases in endogenous serum I,25(OH)2 D3 levels produced by dietary calcium restriction is decreased in elderly women as compared with young women.

为了验证存在内在肠道缺陷的假设， 确定肠道对增加的 膳食钙引起的内源性血清I，25（OH）2D3水平 与年轻妇女相比，老年妇女的限制减少了。