NEW ORLEANS COOP AGREEMENT FOR AIDS CMTY OUTREACH/INTERV

新奥尔良艾滋病合作协议 CMTY 外展/INTERV

• 批准号: 3550437
• 负责人: VERNON J SHORTY
• 金额: $ 37.03万
• 依托单位: DESIRE NARCOTIC REHABILITATION CENTER
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-09-30 至 1996-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3550437
• 关键词: AIDS /HIV test; AIDS education /prevention; HIV infections; artificial intelligence; behavior modification; community health services; cooperative study; crack cocaine; disease /disorder proneness /risk; drug abuse therapy; education evaluation /planning; housing; human subject; human therapy evaluation; intravenous drug abuse; longitudinal human study; medical outreach /case finding; prostitution; sex behavior; sex partner; social support network

This application proposes to conduct a five-year study to monitor HIV risk behavior and evaluate the effectiveness of an enhanced intervention to combat the spread of HIV infection among targeted populations in New Orleans. The targeted populations include intravenous drug users (IVDUs), prostitutes who trade sex for drugs or money, crack cocaine users, and the sexual partners of IVDUs, prostitutes, and crack users. All participants in the proposed study will be drawn from ten large public housing projects in New Orleans. The study will employ a quasi-experimental design in which the ten housing projects will be matched on important characteristics into pairs. One of each pair of matched projects will be randomly assigned to an experimental (i.e., "enhanced") or control (i.e., "standard") intervention condition. The experimental intervention, which builds upon our recent research experience in community outreach to IVDUs, will consist of (a) a CDC approved "knowledge-based" intervention protocol provided at our outreach office by trained personnel, (b) additional information on HIV prevention provided at our office, and (c) risk reduction skills-building training provided in six "onsite" sessions that will be conducted with participants on their own turf in the housing projects over a 12-week period. Participants who reside in the five housing projects randomly assigned to the control condition will receive the standard CDC intervention only at our outreach office. After 30 months, the enhanced intervention will be extended to persons drawn from the housing projects in the control condition. Outcome measures will consist primarily of indicators of HIV risk behavior as measured by NIDA's AIA and AFA. In addition, we will assess other potentially important outcomes, such as psychological adjustment, readiness for drug treatment, number and length of drug treatment episodes, etc. Process measures will include assessment of level of treatment implementation and across-condition contamination. Multi- variate and tabular analyses will be used to assess the initial comparability of participants from the pairs of housing projects, measure the reactivity of the AIA and AFA with the intervention, and evaluate the effectiveness of the enhanced intervention. The evaluation will consider the extent of exposure to the enhanced intervention as well as significant differences between the baseline characteristics of participants from the two conditions in each housing project pair.

这项申请建议进行一项为期五年的研究，以监测艾滋病毒 风险行为，并评估强化干预措施的有效性 防止艾滋病毒感染在新几内亚目标人群中蔓延 奥尔良 目标人群包括静脉注射吸毒者 （静脉吸毒者），卖淫者，以性换取毒品或金钱，快克可卡因 使用者，以及静脉注射吸毒者、妓女和快克使用者的性伴侣。 这项研究的所有参与者将来自10个大型 新奥尔良的公共住房项目。 这项研究将采用准实验设计，其中10个 住房项目将匹配的重要特点， 对. 每对匹配的项目中将随机分配一个 到实验性的（即，“增强的”）或对照（即，“标准”） 干预条件 实验性干预，建立 根据我们最近在社区外展IVDU方面的研究经验， 包括（a）疾病预防控制中心批准的“以知识为基础”的干预方案 （B）由受过训练的人员在我们的外展办事处提供， 我们办公室提供的艾滋病毒预防信息，以及（c）风险 在六次“现场”会议上提供减少排放技能建设培训 这将与参与者在他们自己的地盘上进行， 在12周的时间内完成住房项目。 居住在 五个住房项目随机分配到控制条件将 只在我们的外展办公室接受标准的CDC干预。 30个月后，强化干预将扩大到 从控制条件的住房项目得出。 成果计量将主要包括艾滋病毒风险指标 行为由NIDA的AIA和AFA测量。 此外，我们将评估 其他潜在的重要结果，如心理调整， 戒毒准备情况、戒毒次数和时间长度 过程措施将包括评估 治疗实施和跨条件污染。 多重 变量和表格分析将用于评估初始 两个住房项目参与者的可比性， 测量AIA和AFA对干预措施的反应性，以及 评估强化干预措施的有效性。 评价 将考虑加强干预的风险程度， 以及基线特征之间的显著差异， 参与者从两个条件在每个住房项目对。