BLOOD STORAGE PATTERNS AND RED CELL CONTAMINATION BY YERSINIA ENTEROCOLITICA

最近给疾病控制中心的报告记录了10例败血性休克， 其中7人因输注红细胞而死亡 被小肠结肠炎耶尔森菌污染 这些事件与 单位超过25天。 减少约会的可能性 储存红细胞25天被认为是一种潜在的手段， 降低了受污染单元的输血风险。 获得 关于这种变化对血液供应的预期影响的信息，a 调查血液储存方式和红细胞污染情况。 2004年， 1991年3月 从大约1600份血液中获得数据。 包括几乎所有主要组织在内的机构， 血液采集和分配。 结合所有的中心和所有的约会 储存单位期间，约20%的国家库存， 发现rbc储存超过28天，表明存在严重错位 如果约会时间缩短的话。 只有一个新的病例 对Y的反应确定了小肠结肠炎，表明 事先报告。 这些数据有助于决定由血液 产品咨询委员会，1991年5月，不建议减少约会 对于冰箱储存的RBC。

Recent reports to the CDC have documented ten cases of septic shock, including seven deaths, due to red blood cell (rbc) transfusions contaminated with Yersinia enterocolitica. These incidents were associated with units older than 25 days. The possibility of reducing the dating period to 25 days for stored rbc was considered as a potential means for reducing the risk of transfusion of a contaminated unit. To obtain information on the expected impact on the blood supply of such a change, a questionnaire on blood storage patterns and rbc contamination by Y. enterocolitica was distributed to all registered blood establishments in March, 1991. Data were obtained from approximately 1600 blood establishments including virtually all the major organizations engaged in blood collection and distribution. Combining all centers and all dating periods for stored units, approximately 20% of the national inventory of rbc was found to exceed 28 days of storage, suggesting a major dislocation if the dating period were to be reduced. Only a single new case of adverse reaction to Y. enterocolitica was identified, indicating the adequacy of prior reporting. These data contributed to a decision by the Blood Products Advisory Committee, in May, 1991, not to recommend reduced dating for refrigerator stored rbc.