THE EFFECT OF EARLY VERSUS LATE ONSET OF CHILDHOOD ASTHMA

儿童期哮喘发病年龄的作用存在争议 哮喘 收集的自报医生诊断的哮喘患者的数据 年龄6-24岁（N=376），参加了第二次全国卫生保健 1976年至1980年，一项全国性的 检查是否在2岁或2岁之前发病预测 未来的路。 早发性哮喘患者更有可能 曾因胸部疾病住院的OR = 2.3（95% CI 0.7，6.8），有慢性痰病（OR = 1.6（95%CI 0.8， 3.4），男性OR = 1.7（95% CI 1.0，2.7）。 晚发性哮喘患者 报告更多过敏性鼻炎（OR = 1.5（95% CI 0.8，2.9）， 至少一次阳性皮试（R = 1.5（95%CI 0.7，3.3），报告极好或非常好的健康（R = 1.2，3.7），是白色 OR = 2.2（95% CI 1.1，4.2），居住在城市地区OR = 2（95% CI 1.1， 3.7），家庭收入低于贫困OR = 1.6（95% CI 1.1，2.5）。 没有 差异被发现为报告慢性鼻炎，曾经访问了医学博士 对于胸部状况，报告哮喘处于活动状态， 在过去的12个月里，哮喘，咳嗽发作，或缺课。 的 社会人口统计学和过敏性特征随发病年龄而变化， 但最近的严重性却没有。

Controversy exists as to the role of age of asthma onset in childhood asthma. Data collected on self-reported physician-diagnosed asthmatics ages 6-24 yrs (N=376), who participated in the second National Health and Nutritional Examination, 1976-1980, a national cross-sectional sample, were examined to see if onset at or before age 2 years predicted future course. Early onset asthmatics tended to be more likely to have been ever hospitalized for a chest condition odds ratio (OR) = 2.3 (95% CI 0.7, 6.8), have chronic problems with phlegm (OR = 1.6 (95% CI 0.8, 3.4), be male OR = 1.7 (95% CI 1.0, 2.7). Late onset asthmatics tended to report more allergic rhinitis (OR = 1.5 (95% CI 0.8, 2.9), have at least one positiveprick-puncture allergen skin test (R = 1.5 (95% CI 0.7, 3.3), report excellent or very good health (R = 1.2, 3.7), be white OR = 2.2 (95% CI 1.1, 4.2), live in an urban area OR = 2 (95% CI 1.1, 3.7), have family incomes below poverty OR = 1.6 (95% CI 1.1, 2.5). No difference was found for reported chronic rhinitis, ever visiting an MD for chest condition, reporting asthma to be active, problems within the last 12 months with wheezing, cough attacks, or missing school. The sociodemographic and allergic characteristics varied by age of onset, but recent severity did not.