BIOLOGY AND EXPERIMENTAL THERAPY OF BREAST CANCER

这个多学科的研究计划，从人类学系 肿瘤学和威斯康星州临床癌症中心利用两个实验室 和临床方案，以达到改善治疗的目标， 在疾病的各个阶段都有效。 个别项目 涉及：1）开发乳腺癌特异性克隆测定， 评估其对乳腺癌治疗的预测效果; 2）提高 原发性乳腺癌的整体治疗; 3）了解基本的 激素依赖的生物学和确定的作用机制 用于治疗乳腺癌的雌激素和抗雌激素; 4） 检查人乳腺细胞中的特异性基因座诱变; 5）使用 生物统计支持和基于计算机的数据管理， 研究;以及6）提供适当的行政支援， research.

This multidisciplinary research program from the Department of Human Oncology and the Wisconsin Clinical Cancer Center utilizes both laboratory and clinical programs to achieve the goal of improving therapeutic effectiveness at all stages of the disease. Individual projects are directed at: 1) developing a breast cancer specific clonal assay and evaluating its predictive efficacy for breast cancer therapy; 2) improving the overall treatment of primary breast cancer; 3) understanding the basic biology of hormone dependency and determining the mechanism of action of estrogens and antiestrogens used in the treatment of breast cancer; 4) examining specific locus mutagenesis in human breast cells; 5) use of biostatistical support and computer-based data management to facilitate research; and 6) providing appropriate administrative support to enable the research.