LONG-TERM PLASMA EXCHANGE IN FAMILIAL HYPERCHOLESTEROLEMIA

家族性高胆固醇血症的长期血浆置换

• 批准号: 3884201
• 负责人: EVAN S STEIN
• 金额: --
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3884201
• 关键词: angiography; cardiovascular disorder chemotherapy; clinical trials; familial hyperlipoproteinemia type II; familial hyperlipoproteinemia type III; human subject; human therapy evaluation; longitudinal human study; plasma cells; stroke

The vast majority of the subjects treated under this protocol ere part of the NIH FH Regression Study. Half the group were on drug therapy and repeated plasma change and 1/2 on drug therapy only. Subjects undergo coronary angiography at entry, 2, and 6 years. Initially 34 subjects were entered into the study - 17 in each group and twenty-nine underwent the 4 year angiography. Three subjects has bypass surgery, one had a stroke and the other dropped out. This study has now been completed and results will be published.

根据本方案治疗的绝大多数受试者是 NIH FH回归研究。 一半的人在接受药物治疗， 反复血浆变化和1/2仅接受药物治疗。 受试者经历 入组时、2年和6年时的冠状动脉造影。 最初有34名受试者 进入研究-每组17人，29人接受了4 年的血管造影。 三名受试者做了搭桥手术，一名中风， 另一个退出了 这项研究现已完成，结果将 被公开.