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RENAL PHOSPHATE HANDLING AND BONE DENSITY IN CHILDHOOD CHOLESTASIS

RENAL PHOSPHATE HANDLING AND BONE DENSITY IN CHILDHOOD CHOLESTASIS
儿童胆汁淤积症的肾脏磷酸盐处理和骨密度
批准号：
3884431
负责人：
J NEVIN ISENBERG
金额：
$0.0万
依托单位：
UNIVERSITY OF TEXAS MED BR GALVESTON
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3884431
关键词：
bile obstruction bone density child (0-11) human subject kidney function malabsorption phosphates phosphorus metabolism disorders

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英文摘要
Parathyroid hormone independent renal phosphate wasting has been observed in children with chronic cholestatic liver disease. A correlation between this loss from the phosphate pool and bone density is hypothesized. Age appropriate control groups for renal phosphate handling and bone density (dual photon absorptiometry) will be established. Data from children with protracted cholestasis and from children with malabsorption due to other causes (e.g., cystic fibrosis) can then be compared to the control data.
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