HYPOGLYCEMIA, MATERNAL AND PERINATAL MORBIDITY

低血糖、孕产妇和围产期发病率

• 批准号: 3884203
• 负责人: MICHAEL A BERK
• 金额: --
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3884203
• 关键词: adrenergic receptor; drug administration rate /duration; embryo /fetus disorder; epinephrine; gestational diabetes mellitus; hormone regulation /control mechanism; human morbidity; human subject; hypoglycemia; insulin dependent diabetes mellitus

Clinical trials addressing diabetes and pregnancy have emphasized effects of hyperglycemia on maternal morbidity and neonatal outcome. This prospective study will evaluate the consequences of impaired adrenergic hormonal (epinephrine) counterregulatory responses to hypoglycemia and examine longer term adrenergic adaptation to intensive insulin therapy as is employed in the IDDM pregnancy.

针对糖尿病和怀孕的临床试验强调了疗效 高血糖对产妇发病率和新生儿结局的影响。这 前瞻性研究将评估肾上腺素能受损的后果 激素(肾上腺素)对低血糖和 检查强化胰岛素治疗的长期肾上腺素能适应情况 受雇于IDDM妊娠。