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ATP & PHOSPHO-CREATINE METABOLISM IN X-LINKED HYPOPHOSPHATEMIC RICKETS

ATP & PHOSPHO-CREATINE METABOLISM IN X-LINKED HYPOPHOSPHATEMIC RICKETS
ATP
批准号：
3884116
负责人：
JAMES C.M. CHAN
金额：
$0.0万
依托单位：
VIRGINIA COMMONWEALTH UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3884116
关键词：
1,25 dihydroxycholecalciferol adenosine triphosphate aminoacid metabolism creatine phosphate crosslink human subject muscle disorders vitamin D resistant rickets vitamin therapy

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中文摘要
翻译
确定在X连锁遗传性肌病儿童中观察到的肌病恢复情况， 接受1，25-二羟维生素D3和磷酸盐治疗的低磷酸盐血症佝偻病 与细胞内ATP和磷酸肌酸活性增加有关， 并将这些变化与在相同患者中观察到的变化进行比较， 停药后的稳定状态。
英文摘要
To determine if recovery of myopathy observed in children with X-linked hypophosphatemic rickets receiving 1,25-dihydroxyvitamin D3 and phosphate is related to increased intracellular ATP and phosphocreatine activity, and to compare these changes with those observed in the same patients in the steady state after withdrawal of these medications.
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会议论文
POST-TRANSPLANT GROWTH FAILURE AND VITAMIN D THERAPY
VITAMIN D RESISTANT RICKETS
GROWTH FAILURE WITH RENAL DISEASE IN CHILDREN
GROWTH FAILURE WITH RENAL DISEASE IN CHILDREN
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