BIOMEDICAL RESEARCH SUPPORT

这项提议代表了该部的一项重大新举措。 加州大学伯克利分校化学分校 计算图形网络和可视化设施。它是直接的 具体目标是提供一个环境，让所有人 各部门在生物医学相关科学领域的研究人员可以可视化 关于分子结构和结构的复杂实验或模拟数据 动力学。教职员工将与校园超级计算机对接 并与化学学院X射线晶体实验室合作。会的 提供必要的高级最先进的硬件和软件， 以及使用可视化技术的培训。以这种方式 该设施将被大量的人有效地使用，并将 鼓励以前没有经验的用户参与 视觉化。对用户群体的研究说明清楚地表明 将复杂的、有时是动态的过程可视化的能力 变得极其重要。它将增强我们确定 蛋白质和核酸的结构。蛋白质的设计与研究 非天然氨基酸和催化抗体的设计将是 得到了帮助。脂双分子层动力学和电子传递的研究 在生物系统中，将由快速图形渲染设备来支持。 然而，从长远来看，综合部门设施和网络 因为可视化将对 这项研究是在伯克利化学系进行的。理论与实践 实验研究小组将在#年讨论他们的具体需求 分子结构和动力学的可视化和分析。这将是 推动新一代计算工具的发展 适用于生物医学科学的研究。

This proposal represents a major new initiative by the Department of Chemistry, University of California at Berkeley, to establish a Computational Graphics Network and Visualization Facility. Its immediate and specific aims are to provide an environment where all of the departments' researchers in the Biomedically related sciences can visualize complex experimental or simulation data about molecular structure and dynamics. The faculty will be interfaced with the Campus Supercomputers and with College of Chemistry X-ray Crystallographic Laboratory. It will provide the necessary high-level state-of-the-art hardware and software, as well as training in the use of visualization techniques. In this way the facility will be efficiently used by a large number of people, and will encourage the participation of users who have no previous experience of visualization. The research descriptions of the user group make clear that the ability to visualize complex and sometimes dynamical processes has become extremely important. It will enhance our capacity to determine the structure of proteins and nucleic acids. The design of proteins with unnatural amino acids, and the design of catalytic antibodies will be aided. Studies on the dynamics of the lipid-bilayer and electron transport in biological systems will be supported by fast graphics rendering devices. However, in the long term, the Integrated Departmental Facility and Network for Visualization will have a more profound effect on the nature of research carried out in the Chemistry Department at Berkeley. Theory and experimental research groups will discuss their specific needs in visualization and analysis of molecular structure and dynamics. This will stimulate the evolution of a new generation of computational tools appropriate for research in the Biomedical Sciences.