BIOMEDICAL RESEARCH SUPPORT

生物医学研究支持

• 批准号: 3516038
• 负责人: ROBERT CANCRO
• 金额: $ 3.13万
• 依托单位: NATHAN S. KLINE INSTITUTE FOR PSYCH RES
• 依托单位国家: 美国
• 财政年份: 1979
• 资助国家: 美国
• 起止时间: 1979-04-01 至 1991-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3516038
• 关键词: health science research support

This proposal represents a major new initiative by the Department of Chemistry, University of California at Berkeley, to establish a Computational Graphics Network and Visualization Facility. Its immediate and specific aims are to provide an environment where all of the departments' researchers in the Biomedically related sciences can visualize complex experimental or simulation data about molecular structure and dynamics. The faculty will be interfaced with the Campus Supercomputers and with College of Chemistry X-ray Crystallographic Laboratory. It will provide the necessary high-level state-of-the-art hardware and software, as well as training in the use of visualization techniques. In this way the facility will be efficiently used by a large number of people, and will encourage the participation of users who have no previous experience of visualization. The research descriptions of the user group make clear that the ability to visualize complex and sometimes dynamical processes has become extremely important. It will enhance our capacity to determine the structure of proteins and nucleic acids. The design of proteins with unnatural amino acids, and the design of catalytic antibodies will be aided. Studies on the dynamics of the lipid-bilayer and electron transport in biological systems will be supported by fast graphics rendering devices. However, in the long term, the Integrated Departmental Facility and Network for Visualization will have a more profound effect on the nature of research carried out in the Chemistry Department at Berkeley. Theory and experimental research groups will discuss their specific needs in visualization and analysis of molecular structure and dynamics. This will stimulate the evolution of a new generation of computational tools appropriate for research in the Biomedical Sciences.

该提案是商务部的一项重大新举措 加州大学伯克利分校化学系建立 计算图形网络和可视化设施。 其直接的 具体目标是提供一个环境，让所有 生物医学相关科学部门的研究人员可以可视化 有关分子结构的复杂实验或模拟数据 动力学。 教师将与校园超级计算机连接 并设有化学学院X射线晶体学实验室。 它将 提供必要的高水平、最先进的硬件和软件， 以及使用可视化技术的培训。 这样 该设施将被大量人员有效使用，并将 鼓励没有经验的用户参与 可视化。 用户组的研究描述清楚地表明 可视化复杂且有时是动态过程的能力 变得极其重要。 它将增强我们确定 蛋白质和核酸的结构。 蛋白质的设计 非天然氨基酸，催化抗体的设计将是 协助。 脂质双层和电子传输动力学研究 在生物系统中将得到快速图形渲染设备的支持。 然而，从长远来看，综合部门设施和网络 可视化将对事物的本质产生更深远的影响 研究在伯克利化学系进行。 理论与 实验研究小组将讨论他们的具体需求 分子结构和动力学的可视化和分析。 这将 刺激新一代计算工具的发展 适用于生物医学科学研究。