ENTERAL HORMONAL RESPONSES AND NECROTIZING ENTEROCOLITIS IN PRETERM INFANTS

早产儿的肠道激素反应和坏死性小肠结肠炎

• 批准号: 3905458
• 负责人: ENRIQUE GRISONI
• 金额: --
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3905458
• 关键词: colitis; disease /disorder proneness /risk; gastrointestinal circulation; gastrointestinal hormones; gastrointestinal motility /pressure; hormone regulation /control mechanism; human subject; premature infant human; vasoactive intestinal peptide

Necrotizing enterocolitis is a major clinical problem in neonatal intensive care units in the US. The hypothesis of this study is that newborns with exaggerated gastrointestinal hormone responses, particularly those hormones having their effect on gut motility and gut vasculature, may be at increased risk for the development of necrotizing enterocolitis.

坏死性小肠结肠炎是新生儿的主要临床问题 美国的重症监护室。 本研究的假设是 胃肠激素反应过度的新生儿， 特别是那些对肠道蠕动有影响的激素 肠道血管系统，可能面临更高的发展风险 坏死性小肠结肠炎。