SQUID SUSCEPTOMETER FOR METALLOPROTEIN STUDIES

量子设计超导磁感仪将投入使用 由明尼苏达大学NIGMS资助的四个研究小组。 该仪器将设在格雷淡水生物馆 (GFWBI)，并将被用作 多种金属蛋白的磁化研究。这个 磁化测量将与EPR结合使用， 只要有可能，穆斯堡尔光谱仪就能充分地表征 金属质点稳定氧化还原态的磁性。这个 Proposal仪器是完全自动化的，可以精确地 宽温度下高达5特斯拉的外场磁化强度 范围从1.8K到400D。物理学中的一种可比仪器 明尼苏达大学主校区的系现在 一年365天，每天24小时都在跑步。不到这个数字的三分之一 由于其他方面的需求，金属蛋白研究有时间可用 用户。在高技术领域，需求正在迅速增长 温度超导体。还需要第二台仪器。 明尼苏达大学满足这两个人日益增长的需求 磁化研究的发展领域--金属蛋白和高密度脂蛋白 温度超导体。拟议的(第二)文书将是 位于GFWBI分配给校长的实验室空间 研究人员，将致力于金属蛋白研究。

A Quantum Design superconducting susceptometer will be acquired for use by four research groups funded by NIGMS at the University of Minnesota. The instrument will be located at the Gray Freshwater Biological Institute (GFWBI) and will be used as a primary research tool in the study of the magnetization of a variety of metalloproteins. The magnetization measurements will be used in combination with EPR and, whenever possible, Mossbauer spectroscopies to characterize fully the magnetic properties of the metalloprotiens' stable redox states. The propose instrument is completely automated and makes precision magnetization in applied fields up to 5 Tesla over the broad temperature range from 1.8K to 400D. A comparable instrument located in the Physics Department on the Main Campus of the University of Minnesota is now running 24 hours a day, 365 days a year. Less than one-third of this time is available for metalloprotein studies due to the demands of other users. Rapidly growing demand is developing in the field of high temperature superconductors. A second instrument is needed at the University of Minnesota to meet the increasing demands of these two growing areas of magnetization research - metalloproteins and high temperature superconductors. The proposed (second) instrument will be located at the GFWBI in laboratory space assigned to the Principal Investigator and will be dedicated to metalloprotein studies.