SQUID SUSCEPTOMETER FOR METALLOPROTEIN STUDIES

用于金属蛋白研究的鱿鱼感受器

• 批准号: 3520530
• 负责人: EDMUND P DAY
• 金额: $ 13.4万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-07-06 至 1990-07-05
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3520530
• 关键词: Mossbauer spectrometry; biomagnetism measurement; biomedical equipment purchase; electron spin resonance spectroscopy; magnetism; metalloproteins

A Quantum Design superconducting susceptometer will be acquired for use by four research groups funded by NIGMS at the University of Minnesota. The instrument will be located at the Gray Freshwater Biological Institute (GFWBI) and will be used as a primary research tool in the study of the magnetization of a variety of metalloproteins. The magnetization measurements will be used in combination with EPR and, whenever possible, Mossbauer spectroscopies to characterize fully the magnetic properties of the metalloprotiens' stable redox states. The propose instrument is completely automated and makes precision magnetization in applied fields up to 5 Tesla over the broad temperature range from 1.8K to 400D. A comparable instrument located in the Physics Department on the Main Campus of the University of Minnesota is now running 24 hours a day, 365 days a year. Less than one-third of this time is available for metalloprotein studies due to the demands of other users. Rapidly growing demand is developing in the field of high temperature superconductors. A second instrument is needed at the University of Minnesota to meet the increasing demands of these two growing areas of magnetization research - metalloproteins and high temperature superconductors. The proposed (second) instrument will be located at the GFWBI in laboratory space assigned to the Principal Investigator and will be dedicated to metalloprotein studies.

将购置一台Quantum Design超导磁强计供使用 由明尼苏达大学NIGMS资助的四个研究小组完成。 该仪器将位于灰色淡水生物 研究所（GFWBI），并将作为主要的研究工具， 对各种金属蛋白质磁化的研究。 的 磁化测量将与EPR结合使用， 只要有可能，穆斯堡尔谱充分表征 金属蛋白稳定氧化还原态的磁性。 的 建议的仪器是完全自动化的， 在宽温度范围内，在高达5特斯拉的外加磁场中的磁化强度 范围从1.8K到400 D。 一个类似的仪器位于物理 明尼苏达大学主校区的系现在是 一年365天，每天24小时运转 其中不到三分之一 时间是可用于金属蛋白质的研究，由于其他需求 用户. 快速增长的需求正在发展中的领域， 高温超导体 需要第二台仪器， 明尼苏达大学，以满足这两个日益增长的需求 磁化研究的增长领域-金属蛋白和高 高温超导体 拟议的（第二项）文书将是 位于GFWBI分配给负责人的实验室空间内 研究员，并将致力于金属蛋白研究。