EFFECTS OF PROGESTERONE ON CEH IN THE SLA INBRED MINIATURE PIG

黄体酮对 SLA 近交小型猪 CEH 的影响

• 批准号: 3937276
• 负责人: K J LIPETZ
• 金额: --
• 依托单位: DIVISION OF RESEARCH SERVICES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3937276
• 关键词: fertility; hyperplasia; miniature swine; progesterone; uterus disorder; veterinary medicine

The SLA inbred miniature pig herd, bred and maintained by the Ungulate Unit for the immunology Branch, NCl typically produces a small litter and exhibits a variety of reproductive problems not found in the standard-sized pig. A uterine condition, cystic endometrial hyperplasia (CEH), exists in the herd and is directly involved in reducing the reproductive efficiency of the herd. Sows that are not bred until after one year of age have a high incidence of CEH and are incapable of reproduction. Regression or reduction of the incidence of CEH would improve greatly the reproductive performance of the herd. Previous studies have shown the SLA inbred miniature pig has a serum progesterone level considerably lower than the standard-sized pig. The effects of long term administration of progesterone of CEH will be studied.

SLA近交系小型猪群，由 NCL免疫学分部的有蹄类单位通常会产生 小杂物和表现出各种生殖问题不 在标准大小的猪身上发现的。子宫症、囊肿症 子宫内膜增生症(CEH)，存在于羊群中，直接 与降低牛群的繁殖效率有关。母猪 直到一岁以后才繁殖的幼崽发病率很高 并不具备繁殖能力。回归或还原 CEH发病率的降低将极大地改善生殖 牛群的表现。此前的研究表明，二语习得 近交系小型猪的血清孕酮水平相当高。 低于标准大小的猪。长期的影响 将对CEH的孕酮给药进行研究。