Depression and risk of coronary heart disease: A prospective study of mediating haemostatic risk factors

抑郁与冠心病风险：介导止血危险因素的前瞻性研究

• 批准号: nhmrc : 153716
• 负责人: E/Pr Christopher Tennant
• 金额: $ 21.85万
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2001
• 资助国家: 澳大利亚
• 起止时间: 2001-01-01 至 2003-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/depression-risk-coronary-risk-factors/95986
• 关键词: Depression; risk; coronary; heart; disease

Growing evidence suggests that depression, anger and anxiety play a role in causing coronary heart disease (CHD) and complicating the outcome in existing CHD. This may occur by effects of these emotions on promoting blood clotting and the stickiness of platelets - the blood cells responsible for blood clotting. This pilot study will follow a group of people with depression but without CHD and a control group over 8 months to compare how the blood clotting profile changes as depression resolves. The potential benefits of this research are a better understanding of the links between the common illnesses of depression and CHD that might improve the prevention and treatment of heart disease.

越来越多的证据表明，抑郁、愤怒和焦虑会导致冠心病 (CHD) 并使现有冠心病的结果变得复杂化。这可能是由于这些情绪对促进血液凝固和血小板（负责血液凝固的血细胞）粘性的影响而发生的。这项试点研究将对一组患有抑郁症但没有先心病的患者和对照组进行为期 8 个月的跟踪研究，以比较随着抑郁症消退，凝血功能如何变化。这项研究的潜在好处是更好地了解抑郁症和先心病等常见疾病之间的联系，这可能会改善心脏病的预防和治疗。