UPDATES FOR MICROCHEMICAL FACILITY

怀俄明大学的微型化学设施已经被 现在已经运营了三年。目前提供的服务 包括：1)蛋白质-肽序列，2)氨基酸分析 水解液和生理液，3)DNA合成，4) 多肽合成。DNA测序及氨基酸分析 12名校园调查人员在4个月内使用了这些服务 各部门和20名校外调查人员来自 许多其他机构。一个影响效率的关键因素 而这个实验室的生产力一直是技能和 两家运营商的敬业精神。然而，很明显，他们的 产能已经达到，解决方案仍在继续 该设施的最佳操作是将测序器更新为 包括自动化的在线PTH分析和具有 自动化，灵活的化学氨基酸分析仪。这些都是 本建议书中要求的项目。有四个主要用户和一个 校内和校外的大量次要用户。

The Microchemical facility at the University of Wyoming has been operating for three years now. Services available currently include: 1) protein-peptide sequencing, 2) amino acid analyses both hydrolysis and physiologic fluid, 3) DNA synthesis, and 4) peptide synthesis. The sequencing and amino acid analysis services have been used by twelve on-campus investigators in four departments and by twenty off-campus investigators from numerous other institutions. A critical factor in the efficiency and productivity of this laboratory has been the skill and dedication of the two operators. However, it is clear that their capacity has been reached and the solution to the continued optimal operation of this facility is to update the sequencers to include the automated on-line PTH analyzes and to have an automated, flexible chemistry amino acid analyzer. Those are the items requested in this proposal. There are four major users and a large number of minor users both on- and off-campus.