Bipolar -II Disorder

双相-II型障碍

• 批准号: G0800621/1
• 负责人: Nicol Ferrier
• 金额: $ 83.23万
• 依托单位: Newcastle University
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2009
• 资助国家: 英国
• 起止时间: 2009 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G0800621%2F1
• 关键词: Bipolar; II; Disorder

Bipolar Disorder (also called Manic Depression) is a common metal health problem that affects about 1 in 50 persons. There are actually two types of Bipolar Disorder: Bipolar I disorder and Bipolar II disorder: Bipolar I disorder is the classically described form of manic depression with periods of elation and depression. There is a large and growing body of research on this form of Bipolar Disorder and the best treatment options that may help in both the short-term and longer-term. In recent years it has become apparent that the second form of Bipolar Disorder, Bipolar II disorder is actually more common and, although the ?highs? (symptoms of mania) are less severe, the symptoms of depression are more persistent and disabling than in Bipolar I disorder. Unfortunately, Bipolar II disorder is hardly ever the main focus of research studies and so there are major gaps in our knowledge of how the problem develops over time and we are unclear about the best treatment options. This project proposes to seek the collaboration of 180 individuals with Bipolar II disorder attending both hospital and primary care services. We will study the natural course of this problem using e.g. self-rated diaries, as well as offering people involved in the project the opportunity to receive new medications or psychological treatments by inviting them to take part in small treatment trials. Participants and their carers will play an active part in deciding which studies are the most important to undertake in order to improve the quality of life for patients and their families. Also individuals and their families will be offered the opportunity to attend introductory talks about Bipolar II disorders to let everyone share information about this problem. A series of talks by the researchers will also be offered to keep people involved in the studies up to date with the findings of the project.

双相情感障碍（也称为躁狂抑郁症）是一种常见的金属健康问题，影响约50人中的1人。实际上有两种类型的双相情感障碍：双相I型障碍和双相II型障碍：双相I型障碍是躁狂抑郁症的经典描述形式，具有抑郁和抑郁的时期。关于这种形式的双相情感障碍和最佳治疗方案的研究越来越多，可能有助于短期和长期。近年来，很明显，双相情感障碍的第二种形式，双相情感障碍II实际上是更常见的，虽然？高点？与双相情感障碍I相比，躁狂症（躁狂症的症状）不那么严重，抑郁症的症状更持久和致残。不幸的是，双相II型障碍几乎从来都不是研究的主要焦点，因此我们对问题如何随着时间的推移而发展的知识存在重大差距，我们不清楚最佳治疗方案。该项目建议寻求180名患有双相II型障碍的患者的合作，这些患者同时参加医院和初级保健服务。我们将研究这个问题的自然过程，例如使用自评日记，以及为参与项目的人提供接受新药物或心理治疗的机会，邀请他们参加小型治疗试验。参与者及其护理人员将积极参与决定哪些研究是最重要的，以提高患者及其家属的生活质量。此外，个人和他们的家人将有机会参加有关双相II型障碍的介绍性会谈，让每个人分享有关这个问题的信息。研究人员还将举行一系列讲座，让参与研究的人们了解项目的最新发现。