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Computational modelling of cell movement and chemotaxis

Computational modelling of cell movement and chemotaxis
细胞运动和趋化性的计算模型
批准号:
G0802579/1
负责人:
Robert Insall
金额:
$11.94万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2009
资助国家:
英国
项目状态:
已结题
起止时间:
2009 至 --

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中文摘要
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英文摘要
Cell movement is important in health and in disease. In health, white blood cells must migrate out of blood vessels and through tissues to where they are needed. Conversely, if cells move when they should not, it can cause great harm - the most obvious example is metastasis, when a cancer spreads from a tumour to distant parts of the body. Despite this cell movement is poorly understood. We propose to build a computer model that accurately mimics cell movement, and to use it to sort, test and validate different theories of how cells move. We also propose to train a mathematics expert so he can cross over into the biology field.
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会议论文
How does the Scar/WAVE complex control actin protrusions and cell migration? A combined cell biology and cryo-EM approach.
  • 批准号:
    MR/X000702/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $204.36万
  • 财政年份:
    2023
  • 负责人:
    Robert Insall
  • 依托单位:
How does the Scar/WAVE complex control actin protrusions and cell migration? A combined cell biology and cryo-EM approach.
  • 批准号:
    MR/X000702/2
  • 项目类别:
    Research Grant
  • 资助金额:
    $188.5万
  • 财政年份:
    2023
  • 负责人:
    Robert Insall
  • 依托单位:
Control of cell movement, chemotaxis and the actin cytoskeleton by Scar/WAVE: A genetic analysis using Dictyostelium
SCAR Phosphorylation in the Regulation of Cell Movement - an Analysis Using Dictyostelium
  • 批准号:
    G0600249/2
  • 项目类别:
    Research Grant
  • 资助金额:
    $28.03万
  • 财政年份:
    2007
  • 负责人:
    Robert Insall
  • 依托单位:
国内基金
海外基金
Improving modelling of compact binary evolution.
  • 批准号:
    10903001
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    20.0万元
  • 批准年份:
    2009
  • 负责人:
    史蒂芬
  • 依托单位: