CHEMICAL RESEARCH IN THE DEVELOPMENT OF NEW ANTICANCER DRUGS
CHEMICAL RESEARCH IN THE DEVELOPMENT OF NEW ANTICANCER DRUGS
批准号:
3963199
负责人:
J S DRISCOLL
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
NAD(H) analog acetamides antiviral agents azacitidine aziridines cell differentiation chemical structure function cytidine cytosine arabinoside diazepine drug adverse effect drug design /synthesis /production drug metabolism drug screening /evaluation gas chromatography high performance liquid chromatography hydantoins myelogenous leukemia neoplasm /cancer pharmacology nitrogen mustard nucleoside analog phosphonate pyrimidine analog
中文摘要
合成了许多HMBA类似物,并对其进行了区分评价
英文摘要
A number of HMBA analogs were synthesized and evaluated as differentiating
agents in the in vitro HL-60 cell system. Several compounds were as
effective and potent as HMBA but none were clearly superior.
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CHEMICAL RESEARCH IN THE DEVELOPMENT OF NEW ANTICANCER DRUGS
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批准号:4692071
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
DIDEOXYNUCLEOSIDES AS POTENTIAL ANTI-AIDS DRUGS
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批准号:3939502
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
CNS TARGETED ANTIHIV AGENTS
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批准号:2463802
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
FLUORONUCLEOSIDES AS CNS TARGETED ANTIHIV AGENTS
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批准号:6161092
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
CHEMICAL RESEARCH IN THE DEVELOPMENT OF NEW ANTICANCER DRUGS
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批准号:3896308
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
FLUORONUCLEOSIDES AS CNS TARGETED ANTIHIV AGENTS
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批准号:6100992
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
CHEMICAL RESEARCH IN THE DEVELOPMENT OF NEW ANTICANCER DRUGS
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批准号:3916541
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
DIDEOXYNUCLEOSIDES AS POTENTIAL ANTI-AIDS DRUGS
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批准号:3963220
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
CHEMICAL RESEARCH IN THE DEVELOPMENT OF NEW ANTICANCER DRUGS
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批准号:3939491
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位: