'Azithromycin before Birth'- Single dose azithromycin shortly before birth to reduce infection in Aboriginal mothers and babies: a randomised controlled trial.

“出生前服用阿奇霉素”——在出生前不久服用单剂量阿奇霉素以减少原住民母亲和婴儿的感染：一项随机对照试验。

• 批准号: nhmrc : 2001751
• 金额: $ 320.51万
• 依托单位国家: 澳大利亚
• 项目类别: Clinical Trials and Cohort Studies Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2026-12-31
• 项目状态: 未结题
• 来源: https://researchdata.edu.au/azithromycin-birth-single-controlled-trial/1780938
• 关键词: Azithromycin; before; Birth; Single; dose

Aboriginal mothers and babies in the Northern Territory have high rates of infection. A single dose of azithromycin given during labour (or prior to caesarean section) may reduce the rates of subsequent bacterial infection. This pragmatic clinical trial ('Azithromycin before Birth') will assess a simple intervention that has the potential to substantially improve health outcomes for women and babies at risk of new bacterial infection after birth.

北领地的土著母亲和婴儿感染率很高。在分娩过程中（或剖腹产前）给予单剂量阿奇霉素可降低随后的细菌感染率。这项实用的临床试验（“阿奇霉素治疗前”）将评估一种简单的干预措施，这种干预措施有可能大大改善出生后有新细菌感染风险的妇女和婴儿的健康状况。