SOCIAL EPIDEMIOLOGY AND CONTROL OF CANCER

社会流行病学和癌症控制

• 批准号: 3092550
• 负责人: SAXON GRAHAM
• 金额: $ 56.96万
• 依托单位: STATE UNIVERSITY OF NEW YORK AT BUFFALO
• 依托单位国家: 美国
• 财政年份: 1975
• 资助国家: 美国
• 起止时间: 1975-09-01 至 1986-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3092550
• 关键词: cancer risk; health surveys; neoplasm /cancer epidemiology; nutrition related neoplasm /cancer; nutrition related tag; socioenvironment

We request renewal of support of this program of research in Social Epidemiology and Control of Cancer. In the area of epidemiology, we would complete analyses on data already collected in the following areas: dietary vitamins, meats, fiber, cruciferous vegetables and other aspects of diet in cancer of the esophagus and larynx, to be studied in cases and controls from Roswell Park Memorial Institute (RPMI); reliability of diet interviewing, based on spouse interviews, diet diaries and 24-hour recall of diet in our Western New York Study; the interrelationships of Herpes Simplex Virus-2, numbers of sex partners and other factors in cancer of the cervix in Los Angeles blacks and Chicanos; epidemiology of melanoma in 450 cases and 450 controls from RPMI. In addition, we wish to continue our ongoing data collection for the epidemiologic study of: cancer of the mouth, esophagus, stomach, larynx, colon, rectum, lung and bladder being carried on among all pathologically confirmed cases in Monroe, Niagara and Erie Counties and controls residing in the neighborhoods of cases; cancer of the testis and penis patients residing in New York State, as compared with controls residing in their neighborhoods; the interaction of oral contraceptives with other risk factors in the epidemiology of breast cancer; a prospective study of cancer among approximately 200,000 physicians and nurses in New York State, emphasizing diet. Throughout the period of study, we would carry on analyses of most of the above named cancers for human genetics relationships. Because many measures that can prevent or control cancer devolve from the epidemiology of those diseases and can involve changes in the human behavior, we are interested in the social and behavioral factors associated with cancer prevention and control. Thus, we wish to complete data collection on our study of the efficacy of breast self-examination (BSE) as revealed by comparing proportions who have done BSE in breast cancer patients with advanced and early lesions. We also plan a study of lower-middle, upper-middle and rural residents of Erie County, building upon our earlier inquiry on blacks, to ascertain their knowledge of cancer.

我们请求延长对社会流行病学研究项目的支持 和癌症控制。在流行病学领域，我们将完成分析 基于已经在以下领域收集的数据：膳食维生素、肉类、 纤维、十字花科蔬菜等饮食在癌症中的作用 食道和喉，在罗斯威尔公园的病例和对照中研究 纪念研究所(RPMI)；饮食访谈的可靠性，以配偶为基础 采访、饮食日记和24小时回忆我们纽约西部的饮食 单纯疱疹病毒2型与性伴数量的相关性研究 以及其他导致洛杉矶黑人和奇卡诺人子宫颈癌的因素； RPMI对450例黑色素瘤患者和450例对照的流行病学调查此外, 我们希望继续进行以下流行病学研究的数据收集工作： 口腔、食道癌、胃癌、喉癌、结肠癌、直肠癌、肺癌和膀胱癌 在门罗、尼亚加拉和门罗的所有病理确诊病例中进行 居住在病例附近的伊利县和控制区；癌症 居住在纽约州的睾丸和阴茎患者与对照组的比较 居住在他们的社区；口服避孕药与 乳腺癌流行病学的其他危险因素；一项前瞻性研究 纽约州约20万名医生和护士罹患癌症， 强调节食。在整个学习期间，我们将进行分析 上面提到的大多数癌症都与人类遗传学有关。 因为许多可以预防或控制癌症的措施是从 这些疾病的流行病学，并可能涉及人类行为的变化，我们 对与癌症相关的社会和行为因素感兴趣 防控。因此，我们希望完成对我们研究的数据收集 通过比较发现乳房自我检查(BSE)的有效性 晚期和早期乳腺癌患者行BSE的比例 损伤。我们还计划对中下层、中上层和农村居民进行研究 在我们先前对黑人的调查的基础上，以确定他们 癌症知识。