Capacity Building in Redox Biology

氧化还原生物学能力建设

• 批准号: MC_PC_15076
• 负责人: Neil Bulleid
• 金额: $ 73.98万
• 依托单位: University of Glasgow
• 依托单位国家: 英国
• 项目类别: Intramural
• 财政年份: 2016
• 资助国家: 英国
• 起止时间: 2016 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MC_PC_15076
• 关键词: Capacity; Building; Redox; Biology

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有提供所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为它包含敏感信息，如个人详细信息。

项目成果

How Are Proteins Reduced in the Endoplasmic Reticulum?

• DOI: 10.1016/j.tibs.2017.10.006
• 发表时间: 2018-01
• 期刊: Trends in biochemical sciences
• 影响因子: 13.8
• 作者: Ellgaard L;Sevier CS;Bulleid NJ
• 通讯作者: Bulleid NJ

Central role of c-Src in NOX5- mediated redox signalling in vascular smooth muscle cells in human hypertension.

• DOI: 10.1093/cvr/cvab171
• 发表时间: 2022-03-25
• 期刊: Cardiovascular research
• 影响因子: 10.8
• 作者: Camargo LL;Montezano AC;Hussain M;Wang Y;Zou Z;Rios FJ;Neves KB;Alves-Lopes R;Awan FR;Guzik TJ;Jensen T;Hartley RC;Touyz RM
• 通讯作者: Touyz RM

Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase.

蛋氨酸亚氧化亚氧化物还原酶B3需要解决半胱氨酸残基以进行全活性，并且可以作为立体特异性蛋氨酸氧化酶。

• DOI: 10.1042/bcj20170929
• 发表时间: 2018-02-28
• 期刊: The Biochemical journal
• 作者: Cao Z;Mitchell L;Hsia O;Scarpa M;Caldwell ST;Alfred AD;Gennaris A;Collet JF;Hartley RC;Bulleid NJ
• 通讯作者: Bulleid NJ

Mix-and-Match Proteomics: Using Advanced Iodoacetyl Tandem Mass Tag Multiplexing To Investigate Cysteine Oxidation Changes with Respect to Protein Expression.

混合匹配蛋白质组学：使用先进的碘乙酰串联质量标签多重技术研究半胱氨酸氧化与蛋白质表达的关系。

• DOI: 10.1021/acs.analchem.8b02517
• 发表时间: 2018
• 期刊: Analytical chemistry
• 影响因子: 7.4
• 作者: Prakash AS

Selective Inhibition of the C-Domain of ACE (Angiotensin-Converting Enzyme) Combined With Inhibition of NEP (Neprilysin): A Potential New Therapy for Hypertension.

• DOI: 10.1161/hypertensionaha.121.17041
• 发表时间: 2021-09
• 期刊: Hypertension (Dallas, Tex. : 1979)
• 作者: Alves-Lopes R;Montezano AC;Neves KB;Harvey A;Rios FJ;Skiba DS;Arendse LB;Guzik TJ;Graham D;Poglitsch M;Sturrock E;Touyz RM
• 通讯作者: Touyz RM