PREDICTIVE VALUE OF THE EEG IN FEBRILE SEIZURES

脑电图对热性惊厥的预测价值

• 批准号: 4696884
• 负责人: L V RUBINSTEIN
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/4696884
• 关键词: Bosnia-Hercegovina; child (0-11); electroencephalography; febrile seizure; human subject; information systems; longitudinal human study; prognosis; relapse /recurrence

This population based study will evaluate the significance of the EEG as a predictor for recurrence of seizures in those children who have had a simple febrile convulsion. Outcome with respect to febrile seizure recurrence and afebrile seizure occurrence will be reported. The evolution of the EEG pattern will be described, and patterns will be correlated with the clinical outcome. The clinical study is being carried out in Skopje, Yugoslavia, at the Pediatric Clinic of the University of Skopje. The study began in FY'82 and will be completed in FY'88. During FY'85 the data management and qulity control systems were revised as needed. By the first quarter of FY'85, approximately 400 patients with a febrile seizure, no prior complex or multiple seizures and with a normal or nonspecific abnormal EEG were registered into the study and began the study protocol and follow-up. An additional 200 patients with a specific abnormal EEG were entered for baseline information and follow-up. Data monitoring, editing and file creation are continuing. Statistical analysis of short-term outcomes and EEG changes will begin in FY'86. Patient accrual was completed in December 1984 and follow-up should be completed on all patients by FY'88.

这项基于人群的研究将评估EEG作为一种 癫痫复发的预测因子， 单纯性热性惊厥 热性惊厥结局 将报告复发和无热性惊厥发生率。 演变 将描述EEG模式，并且模式将与 临床结果。 临床研究正在斯科普里进行， 南斯拉夫，在斯科普里大学儿科诊所。 这项研究于1982财政年度开始，将于1988财政年度完成。 1985年， 根据需要修订了数据管理和质量控制系统。 由 85财年第一季度，约有400名热性癫痫患者， 既往无复杂或多发性癫痫发作， 将异常EEG登记到研究中并开始研究方案 和后续行动。 另外200名患者有特定的异常脑电图 用于基线信息和随访。 数据监测， 编辑和文件创建仍在继续。 统计分析 短期结果和脑电图变化将在86财年开始。 患者累积 已于1984年12月完成，应完成对所有 88年的病人。