Targeting the compromised brain endothelial barrier function during cerebral malaria with AT2 receptor agonists

使用 AT2 受体激动剂针对脑型疟疾期间受损的脑内皮屏障功能

• 批准号: MC_PC_19023
• 负责人: Alan Stitt
• 金额: $ 22.3万
• 依托单位: Queen's University Belfast
• 依托单位国家: 英国
• 项目类别: Intramural
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MC_PC_19023
• 关键词: Targeting; compromised; brain; endothelial; barrier

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

Loss of TRPV2-mediated blood flow autoregulation recapitulates diabetic retinopathy in rats.

• DOI: 10.1172/jci.insight.155128
• 发表时间: 2022-09-22
• 期刊: JCI INSIGHT
• 影响因子: 8
• 作者: O'Hare, Michael;Esquiva, Gema;McGahon, Mary K.;Hombrebueno, Jose Manuel Romero;Augustine, Josy;Canning, Paul;Edgar, Kevin S.;Barabas, Peter;Friedel, Thomas;Cincola, Patrizia;Henry, Jennifer;Mayne, Katie;Ferrin, Hannah;Stitt, Alan W.;Lyons, Timothy J.;Brazil, Derek P.;Grieve, David J.;McGeown, J. Graham;Curtis, Tim M.
• 通讯作者: Curtis, Tim M.

Long term high glucose exposure induces premature senescence in retinal endothelial cells.

• DOI: 10.3389/fphys.2022.929118
• 发表时间: 2022
• 期刊: Frontiers in physiology
• 影响因子: 4

Ocular Biomechanics - A Bright Future.

眼部生物力学 - 光明的未来。

• DOI: 10.1080/02713683.2022.2154807
• 发表时间: 2023
• 期刊: Current eye research
• 影响因子: 2
• 作者: Elsheikh A

Impaired Function in Diabetic Patient iPSCs-derived Blood Vessel Organoids Stem from a Subpopulation of Vascular Cells

• DOI: 10.1101/2022.07.18.500478
• 发表时间: 2022-07
• 期刊: bioRxiv
• 作者: H. Naderi-Meshkin;M. Eleftheriadou;Garret Carney;V. A. Cornelius;Clare-Ann Nelson;Sophia Kelaini

Advances in cell therapies using stem cells/progenitors as a novel approach for neurovascular repair of the diabetic retina.

• DOI: 10.1186/s13287-022-03073-x
• 发表时间: 2022-07-30
• 期刊: Stem cell research & therapy
• 影响因子: 7.5