The risk of a chronic clinical condition following a previous hospitalisation by a psychiatric disorder: a linkage nationwide study in Brazil

先前因精神疾病住院后出现慢性临床疾病的风险：巴西的一项全国性连锁研究

• 批准号: MC_PC_MR/T03355X/1
• 负责人: Mauricio Barreto
• 金额: $ 20.37万
• 依托单位: Oswaldo Cruz Foundation
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MC_PC_MR%2FT03355X%2F1
• 关键词: risk; chronic; clinical; condition; following

Multimorbidity is the occurrence of more than one chronic condition at a time. This can include conditions like cardiovascular disease, a mental health condition of long duration, such as a mood disorder or dementia or an infectious disease of long duration, such as Tuberculosis.Multimorbidity increases with age and also presents certain distinct patterns related to sex. On the other hand, mental disorders are commonly found together and usually have consequences on other chronic physical condition that the patient may have. Mental health disorders, in particular depression, represent an important risk factor for premature mortality. Multimorbidity can also increase the treatment costs, as subjects with depression will cost 50% more to health systems than those with one chronic condition alone. Cardiovascular diseases are also found to co-occur with depression, this might happen because these patients show difficulties in following their GP 's recommendations. It is of note that women seem to be at higher risk of morbidity from cardiovascular disease, while they are also at a higher risk of depression suggesting gender-specific mechanisms. Analysis of a recent health survey in adult Brazilians observed that the prevalence rate of multimorbidity are higher among women compared to men, among older people and those with lower educational level.We at the Center for Data Integration and Knowledge for Health (CIDACS) have access to very large datasets, which would commonly be known as Big Data. This data comprises information from Brazilian subjects that were listed or benefited by one of the several social programmes or were seen in any of the numerous public hospital of the country's universal health system.This project aims at increasing knowledge over the relationship of mental disorders and other chronic conditions to ameliorate the lives of those affected. More specifically we want to (A) estimate the the risk of hospitalisations or death by diabetes mellitus, cardiovascular diseases or stroke following a hospitalisation due to depressive disorders, alcohol and substance use-related disorders, and schizophrenia; (B) To estimate the risk of the occurrence or death by tuberculosis following a hospitalisation due to depressive disorders, alcohol and substance use-related disorders, and schizophrenia; (C) To investigate how these chronic conditions goes together in clusters and how these patterns evolve over time and ageing.

多发病是一次发生一种以上的慢性疾病。这可能包括心血管疾病，长期的心理健康状况，如情绪障碍或痴呆症或长期的传染病，如结核病。多发病随着年龄的增长而增加，也呈现出与性别有关的某些独特模式。另一方面，精神障碍通常会同时出现，并且通常会对患者可能患有的其他慢性身体状况产生影响。心理健康障碍，特别是抑郁症，是过早死亡的一个重要风险因素。多重抑郁症也会增加治疗费用，因为抑郁症患者的医疗费用比仅患有一种慢性疾病的患者高出50%。心血管疾病也被发现与抑郁症同时发生，这可能是因为这些患者在遵循他们的家庭医生的建议方面表现出困难。值得注意的是，妇女患心血管疾病的风险似乎更高，而她们患抑郁症的风险也更高，这表明了性别特有的机制。最近对巴西成年人的健康调查分析发现，与男性相比，女性、老年人和教育水平较低的人中，多发性硬化症的患病率更高。我们在数据集成和健康知识中心（CIDACS）可以访问非常大的数据集，这些数据集通常被称为大数据。这些数据包括巴西受试者的信息，这些受试者被列入若干社会方案之一或从中受益，或在该国全民保健系统的众多公立医院中的任何一家就诊，该项目旨在增加对精神障碍与其他慢性病之间关系的了解，以改善受影响者的生活。更具体地说，我们希望（A）估计因抑郁症、酒精和物质使用相关障碍以及精神分裂症住院后糖尿病、心血管疾病或中风住院或死亡的风险;（B）估计因抑郁症、酒精和物质使用相关障碍以及精神分裂症住院后结核病发生或死亡的风险;（C）调查这些慢性病是如何成组发生的，以及这些模式如何随着时间和年龄的增长而演变。

项目成果

Symptoms of anxiety and depression associated with concerns about infection and gender-based violence during the COVID-19 pandemic

• DOI: 10.23889/ijpds.v7i2.1734
• 发表时间: 2022-03-01
• 期刊: International Journal of Population Data Science
• 作者: Machado DB;da Silva Rodrigues E;Barbosa JR;de Oliveira Alves FJ;Gonçalves AQ;Duarte-Salles T;Aviñó CJ;Berenguera A;Passos MF;Barreto ML;Castro-de-Araujo LF
• 通讯作者: Castro-de-Araujo LF

Construção de conhecimento no curso da pandemia de COVID-19: aspectos biomédicos, clínico-assistenciais, epidemiológicos e sociais

COVID-19 流行病的相关分析：生物医学、临床辅助、流行病学和社会方面

• DOI: 10.9771/9786556300443.010
• 发表时间: 2020
• 作者: Grassi M

Multimorbidity worsened anxiety and depressive symptomatology during the Covid-19 pandemic

Covid-19 大流行期间，多重发病加剧了焦虑和抑郁症状

• 作者: Castro-De-Araujo, LFS

Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019.

• DOI: 10.1016/s2468-2667(21)00249-8
• 发表时间: 2022-03
• 期刊: The Lancet. Public health
• 作者: GBD 2019 Dementia Forecasting Collaborators

Multimorbidity worsened anxiety and depression symptoms during the COVID-19 pandemic in Brazil.

• DOI: 10.1016/j.jad.2022.07.005
• 发表时间: 2022-10-01
• 期刊: JOURNAL OF AFFECTIVE DISORDERS
• 影响因子: 6.6
• 作者: Silva Castro-de-Araujo, Luis Fernando;Rodrigues, Elisangela da Silva;Machado, Daiane Borges;Pessanha Henriques, Claudio Maierovitch;Verotti, Mariana Pastorello;Goncalves, Alessandra Queiroga;Duarte-Salles, Talita;Kanaan, Richard A.;Barreto, Mauricio Lima;Lewis, Glyn;Barbosa, Jakeline Ribeiro
• 通讯作者: Barbosa, Jakeline Ribeiro