Thematic Support - Disease Control and Elimination

专题支持——疾病控制和消除

• 批准号: MC_UU_00031/1
• 负责人: Anna Roca
• 金额: $ 317.7万
• 依托单位: London School of Hygiene & Tropical Medicine
• 依托单位国家: 英国
• 项目类别: Intramural
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=MC_UU_00031%2F1
• 关键词: Thematic; Support; Disease; Control; Elimination

The theme has a large portfolio that includes research aimed to decrease the burden of the most common causes of illness and mortality in the West African region, namely malaria, infections caused by bacteria and infections caused by viruses. From the start of the COVID-19 pandemic, the theme has developed a large portfolio to try to understand the effect of the pandemic in the country and why the severity of the infections has been lower than anticipated. The research conducted by the Theme has generated knowledge in the different areas. Some key examples follow:- Research at the theme works on the control of malaria (to decrease the annual number of cases) and elimination (to reach the 0 cases). In malaria control, the Unit has worked along with the National Malaria Control Program to monitor the efficacy of different anti-malarial medicines and with the results update the National treatment policy of malaria patients. In malaria elimination, the theme has designed novel interventions against malaria in regions where the number of cases is very low (reactive treatment). These studies are important in pre-elimination stages. - Research conducted by the theme has informed national and international policies on the immunization with the Pneumococcal conjugate vaccine. This is important as Pneumococcus is still a main contributor of under-5 mortality in the region.- The Theme provided data for the introduction of the Rotavirus vaccine in the country followed by data on the effect of the vaccine in reducing Rotavirus cases and deaths. - During 2020, the first wave of COVID-19 disease did not increase mortality in the rural areas of the country.

该主题有一个很大的组合，其中包括旨在减轻西非区域最常见的疾病和死亡原因的负担的研究，即疟疾、细菌引起的感染和病毒引起的感染。自2019冠状病毒病大流行开始以来，该主题编制了一个庞大的组合，试图了解大流行对该国的影响，以及为什么感染的严重程度低于预期。主题进行的研究产生了不同领域的知识。以下是一些关键的例子：-本主题的研究工作是控制疟疾（减少每年病例数）和消除疟疾（达到零病例）。在疟疾控制方面，该股与国家疟疾控制规划合作，监测不同抗疟疾药物的疗效，并根据监测结果更新国家疟疾患者治疗政策。在消除疟疾方面，该主题在病例数极低的地区设计了新的疟疾干预措施（反应性治疗）。这些研究在消除前阶段很重要。-根据该主题进行的研究为国家和国际关于肺炎球菌结合疫苗免疫的政策提供了信息。这一点很重要，因为肺炎球菌仍然是该区域5岁以下儿童死亡的主要原因。-主题提供了在该国引进轮状病毒疫苗的数据，然后提供了关于疫苗在减少轮状病毒病例和死亡方面效果的数据。- 2020年期间，第一波COVID-19疫情并未增加该国农村地区的死亡率。