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PHARMACOKINETICS & TOLERANCE OF GANCICLOVIR IN HIV INFECTED CHILDREN

PHARMACOKINETICS & TOLERANCE OF GANCICLOVIR IN HIV INFECTED CHILDREN
药代动力学
批准号：
5217731
负责人：
JOSEPH CHURCH
金额：
$0.0万
依托单位：
--
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/5217731
关键词：
AIDS therapy HIV infections adolescence (12-20) child (0-11) clinical research clinical trials cytomegalovirus drug administration rate /duration drug adverse effect drug screening /evaluation drug tolerance ganciclovir human immunodeficiency virus human subject human therapy evaluation opportunistic infections oral administration pediatric AIDS pediatric pharmacology pharmacokinetics

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中文摘要
翻译
年龄在两周到二十岁之间的艾滋病毒感染者， 本研究招募了100名巨细胞病毒感染者，以评估其安全性和 新的口服药物更昔洛韦的副作用。 这样做的目的 研究是为了确定口服形式的更昔洛韦是否可以耐受 当给予HIV感染的婴儿和CMV儿童24周时， 感染，并确定最大耐受剂量和副作用 口服更昔洛韦的效果。
英文摘要
Individuals between two weeks to twenty years of age who have an HIV and cytomegalovirus are enrolled in this study to evaluate the safety and side effects of a new oral medication, ganciclovir. The purpose of this study is to determine if an oral form of ganciclovir can be tolerated when given for 24 weeks to HIV infected infants and children with CMV infection and to determine what is the maximum tolerable dose and side effects of oral ganciclovir.
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会议论文
IN VIVO ASSESSMENT OF CLINICALLY RELEVANT AUTOANTIBODIES IN IVIG PREPARATIONS
SAFETY AND IMMUNOGENICITY OF OKA/MERCK VARICELLA VIRUS VACCINE IN CHILDREN W/HIV
SAFETY AND IMMUNOGENICITY OF OKA/MERCK VARICELLA VIRUS VACCINE IN CHILDREN W/HIV
SAFETY AND IMMUNOGENICITY OF OKA/MERCK VARICELLA VACCINE
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