UKCRC Joint Funders Tissue Directory and Coordination Centre

UKCRC 联合资助者组织名录和协调中心

• 批准号: MR/M501748/1
• 负责人: Brian Davidson
• 金额: $ 114.52万
• 依托单位: University College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2014
• 资助国家: 英国
• 起止时间: 2014 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MR%2FM501748%2F1
• 关键词: UKCRC; Joint; Funders; Tissue; Directory

Summary of Aims and DeliveryThe main aim of our Coordination Centre is to provide strong leadership in realising the UKCRCFunders' Vision for Human Tissue Resources1, by increasing the quality, visibility and accessibility ofthe UK's world class specimen and cohort collections for academic and commercial researchers. Fourconcepts will form the foundation of our vision: (1) to identify the current limitation to optimalbiobanking amongst a wide range of stakeholders and custodians of research samples; (2) to reachconsensus on optimal solutions to those issues; (3) to implement the changes through three WorkStreams, informatics, harmonisation and engagement; (4) to evaluate project outputs and identifyfuture needs. The project will bring together UCL and University of Nottingham, to provide a worldclassenvironment with wide-ranging engagement of experts from internationally renownedbiobanks.The Coordination Centre will be based in the UCL Office of the Vice Provost for Health and will be ledby Anne Carter who has a strong track record of engaging with biobanking communities to deliverharmonisation and standardisation strategies. This strategic positioning will ensure the centre'sobjectivity by embedding it within an environment already experienced in dealing with multipleinstitutional interests across organisations such as UCL Partners and UCL Bioresource. Theinformatics development and database will be hosted within the University of Nottingham AdvancedData Analysis Centre. Our partnership will align an unrivalled combination of world leading academicinstitutions, with expertise in coordinating national biobanking initiatives, developing novelbiobanking IT systems, and leading public/patient/stakeholder engagement, as demonstrated by theletters of support in Appendix I. The project will also bring together a wide and diverse range ofbiobanks and internationally recognised researchers in informatics and 'omics' activities, forexample, cancer biobanks, eye banks, dental banks, a range of biobanks at the Institute of ChildHealth and Institute of Neurology and a collection of large cohort studies in healthy and diseasepopulations.Our main deliverable will be the development of a robust and scalable web based informaticsplatform with simple functionality, which will be used to link and disseminate information on theinformatics, harmonisation and engagement work streams. Success will depend on effectivelyengaging researchers, biosample collections, the public, regulators and policy makers, so as todevelop an agreed, unified system for the UK. Biobanking groups will benefit by understanding andbeing actively involved in developing a pan-UK system, allowing reliable exchange of humanbiospecimens and associated clinical data. Researchers will gain from increased visibility of, andease of access to appropriate quality assured samples and data, whilst funders will avoid supportingunnecessary bioresources. We will deliver a biobanking system appropriate for internationalbiobanking collaboration.

我们协调中心的主要目标是通过为学术和商业研究人员提高英国世界级标本和队列收藏的质量、可见度和可及性，在实现ukcrc资助者对人体组织资源的愿景方面提供强有力的领导。四个概念将构成我们愿景的基础：(1)确定目前在广泛的研究样本的利益相关者和保管人中对最佳生物银行的限制；(2)就这些问题的最优解决方案达成共识；(3)通过信息学、协调和参与三个工作流程来实施变革；(4)评估项目产出并确定未来需求。该项目将汇集伦敦大学学院和诺丁汉大学，为来自国际知名生物银行的专家提供一个广泛参与的世界级环境。协调中心将设在伦敦大学学院卫生副教务长办公室，由安妮·卡特（Anne Carter）领导，她在与生物银行社区合作以提供协调和标准化战略方面有着良好的记录。这种战略定位将确保该中心的客观性，将其嵌入一个已经在处理跨组织（如UCL Partners和UCL Bioresource）的多机构利益方面经验丰富的环境中。信息学开发和数据库将由诺丁汉大学高级数据分析中心托管。我们的合作伙伴关系将结合世界领先的学术机构，在协调国家生物银行计划、开发新型生物银行IT系统和领导公众/患者/利益相关者参与方面的专业知识，如附录1中的支持信所示。该项目还将汇集广泛多样的生物银行和国际公认的信息学和“组学”活动的研究人员，例如癌症生物银行、眼库、牙科银行，儿童健康研究所和神经病学研究所的一系列生物银行，以及健康和疾病人群的大型队列研究的集合。我们的主要成果将是开发一个具有简单功能的强大且可扩展的基于web的信息平台，该平台将用于链接和传播有关信息学，协调和参与工作流的信息。成功将取决于有效地让研究人员、生物样本收集者、公众、监管机构和政策制定者参与进来，以便为英国开发一个商定的、统一的系统。生物银行组织将通过理解并积极参与开发一个泛英国系统而受益，该系统允许可靠地交换人类生物标本和相关临床数据。研究人员将从增加可见性和获得适当的质量保证的样本和数据的便利中获益，同时资助者将避免支持不必要的生物资源。我们将提供一个适合国际生物银行合作的生物银行系统。

项目成果

Be a biobank: Engaging the public in biobanking through games

成为生物样本库：通过游戏让公众参与生物样本库

• 发表时间: 2016
• 作者: Sims JM

BBMRI.uk: The UK's National Biobanking Node

BBMRI.uk：英国国家生物样本库节点

• 发表时间: 2016
• 作者: Quinlan PR

The UK Clinical Research Collaboration (UKCRC) Tissue Directory and Coordination Centre: The UK's Centre for facilitating the Usage of Human Samples for Medical Research

英国临床研究合作组织 (UKCRC) 组织目录和协调中心：英国促进人体样本用于医学研究的中心

• DOI: 10.5334/ojb.31
• 发表时间: 2017
• 期刊: Open Journal of Bioresources
• 作者: Quinlan P

Gamify Your Biobank: Raising Public Awareness Through Social Game Play

将您的生物库游戏化：通过社交游戏提高公众意识

• 发表时间: 2016
• 作者: Sims JM

Biobanking: the boardgame. Public engagement through table top game development

生物银行：棋盘游戏。

• 发表时间: 2015
• 作者: Sims J