ETHICAL IMPLICATIONS OF GENETIC ENHANCEMENT TECHNOLOGIES

基因技术和知识以前所未有的速度发展，可能会使社会无法就如何利用这些进步提供合理的伦理指导。鉴于科学的复杂性和社会面临的艰难的伦理选择，培养在这两个领域都有专长的个人是非常可取的。考虑到这一目标，本研究计划旨在为Sikela博士（一位成熟的基因组科学家）提供生物医学伦理方面严格而有效的培训经验，特别关注基因增强技术的伦理和社会影响。Drs。Mark Yarborough和Eric Juengst将担任该奖学金的共同发起人。培训经验将主要集中在研究（80%），也有一些时间用于课程作业（15%）和教学（5%）。这项研究将调查与基因增强技术相关的几个关键问题，包括对改变后代基因构成的能力可能带来的伦理挑战的调查。这项研究将包括与赞助者和该领域的其他专家的讨论，阅读相关文献，积极参与与生物医学伦理和基因增强有关的会议、研讨会、课程和教学。这次培训的目的是为Sikela博士提供专业知识，使他能够为社会努力应对这些新出现的伦理问题做出重大贡献。

The unprecedented pace at which genetic technology and knowledge is advancing threatens to overwhelm society's ability to provide sound ethical guidance regarding how such advances should be used. Given the complexity of the science and the difficult ethical choices society is faced with, the development of individuals who have expertise in both areas would be highly desirable. With this goal in mind, this research proposal seeks to provide Dr. Sikela, an established genome scientist, with a rigorous and effective training experience in biomedical ethics, with a specific focus on the ethical and societal implications of genetic enhancement technologies. Drs. Mark Yarborough and Eric Juengst will serve as co-sponsors of the fellowship. The training experience will focus primarily on research (80 percent), with some time also devoted to coursework (15 percent) and teaching (5 percent). The research will investigate several critical issues related to genetic enhancement technology, including an investigation of the ethical challenges that might be posed by the ability to alter the genetic makeup of future generations. The research will be comprised of discussions with sponsors and other experts in the field, reading of relevant literature, and active involvement in conferences, seminars, courses, and teaching that relate to biomedical ethics and genetic enhancement. It is the intent of this training experience to provide Dr. Sikela with the expertise that will allow him to make significant contributions to society's effort to deal with these emerging ethical issues.