HIGH RESOLUTION THREE DIMENSIONAL ULTRASOUND IMAGING

描述(改编自申请者摘要)：总体目标 这项工作的发展是高分辨率、实时、三 三维(3D)超声成像系统。调查人员已经 开发了一种实时体积成像系统，目前正在进行体内试验 测试。使用第四代相控阵系统的初步结果 256个发送和256个接收通道和16：1并行接收处理 显示心肌灌注缺陷的成像能力 并提供左、右室搏动等容量数据 在没有几何假设的情况下，体内体积和左心室质量。当前图像 在12厘米的范围内，分辨率约为65立方毫米，几乎不足以 临床应用。此外，视野被限制在一个 65度金字塔和帧速率约为每秒20。此应用程序 建议开发新的发射和接收技术，以进一步提高 4倍的数据采集率和新的更高频率的2-D 阵列，使体积分辨率净提高10倍。上演的 新一代高分辨率实时体积测量仪的研制 提出了一种基于早期工程试验台的成像系统。新的 多波束传输概念与：1接收处理 并行性将在改进的Duke相控阵成像仪上进行测试，该成像仪 将升级到550个高速发射器和250个频道，全部 数字接收系统。一旦操作概念得到验证， 调查人员建议将这一概念验证系统扩大到1300个 传输和1300接收通道，以实现最终的高质量成像 活着。

DESCRIPTION (Adapted from Applicant's Abstract): The overall objective of this work is the development of high resolution, real time, three dimensional (3-D) ultrasound imaging systems. The investigators have developed a real time volumetric imaging system currently undergoing in vivo testing. Initial results using a fourth generation phased array system with 256 transmit and 256 receive channels and 16:1 parallel receive processing demonstrate the capability of imaging perfusion defects in the myocardium and providing volumetric data such as left and right ventricular stroke volumes and LV mass in vivo without geometric assumptions. Current image resolution is about 65 cubic mm at 12 cm range, which is barely adequate for clinical applications. In addition, the field of view is limited to a 65-degree pyramid and frame rates are about 20 per second. This application proposes to develop new transmit and receive techniques to further increase the data acquisition rate by a factor of 4 and new higher frequency 2-D arrays to permit a net 10-fold improvement in volume resolution. The staged development of a new generation, high-resolution real time volumetric imaging system based on an earlier engineering testbed is proposed. New concepts in multiple beam transmission and 64:1 receive processing parallelism are to be tested on the modified Duke Phased Array imager which would be upgraded to 550 high speed transmitters and a 250 channel, all digital receive system. Once operational concepts have been verified, the investigators proposed to expand this proof-of-concept system to 1300 transmit and 1300 receive channels for eventual high quality imaging in vivo.