Core--Cohort Facility

招募和保留研究对象是研究中最困难的组成部分之一。在处理易受伤害和难以接触到的人口，如市中心少数民族青少年时，这一困难更加严重。招募和保留研究对象可能是劳动密集型和时间密集型的，如果做得不好，可能会阻碍研究人员回答关键科学问题的能力。队列核心的总体目标是为招募、同意、筛选、入组和保留研究受试者提供后勤支持，并根据需要为弗朗西斯科青少年和性病CRC（SFCRC）的所有项目收集适当的访谈和生物学数据。该核心的目标是提供一切必要的支持，以确保SFCRC的各个项目获得实现其特定目标所需的数据。由于将以有组织的方式确定和招募个人，因此可以进行多项研究，而不会在社区内造成混乱。集中招聘模式允许同时实施多项研究以及未来扩展项目，而不会损害为开展初始项目而建立的准入、意识和可接受性。具体而言，该队列核心的目标是：1。从通过随机数字拨号确定的目标人群中招募、同意、筛选和招募青少年指数受试者的随机家庭概率样本9项目1，2，3）2。招募、同意并登记两代青少年索引受试者的性伴侣（项目1、3）。招募、同意、筛选和登记性经验不足的女性青少年指数受试者的女性社会伴侣（项目2、3）。4.跟踪和保留研究受试者进行随访（项目1、2、3）5.确保成功收集研究受试者的访谈数据和生物标本（项目1、2、3）

Recruitment and retention of study subjects is one of the most difficult components of research. This difficulty is compounded when dealing with vulnerable and hard-to-reach populations such as inner-city, minority adolescents. Recruitment and retention of study subjects can be both labor- and time-intensive and if not done properly can impede researchers' ability to answer critical scientific questions. The overall objective of the Cohort Core is to provide the logistical support to recruit, consent, screen, enroll and retain study subjects and to collect the appropriate interview and biological data as needed for all projects of the San Francisco Adolescents and STDs CRC (SFCRC). It is the goal of this Core to provide all necessary support to ensure that the individual projects of the SFCRC receive the data needed to achieve their specific aims. Because individuals will be identified and recruited in an organized manner, multiple studies can be ongoing without creating confusion within the community. A centralized recruitment model allows for the implementation of several studies simultaneously as well as for future expansion of projects without jeopardizing the access, aware and acceptability established to conduct the initial projects. Specifically, the aims of this Cohort Core are to: 1. Recruit, consent, screen, and enroll a random household probability sample of adolescent index subjects from the target population identified through random-digit dialing 9Projects 1, 2, 3) 2. Recruit, consent, and enroll two generations of adolescent index subjects' sex partners (Projects 1, 3) 3. Recruit, consent, screen, and enroll female social partners of sexually inexperienced female adolescent index subjects (Projects 2, 3). 4. Track and retain study subjects for follow-up (Projects 1, 2, 3) 5. Ensure successful collection of interview data and biological specimens from study subjects (Projects 1, 2, 3)