DEVELOPMENTAL TOXICITY OF METHYLMERCURY

描述：该应用程序的主要目标是更好地定义 与出生前和出生后早期接触铅有关的人类健康风险 鱼中的甲基汞。微妙的心理和行为变化将是 测量并与母亲在怀孕期间的暴露有关。这项研究 将对740名儿童进行队列调查，这些儿童来自 塞舌尔群岛，其食物主要是大量的海洋 鱼。这项应用将延长对发育毒性的评估 在队列中包括7-8岁的甲基汞，这将是 使结果与产前研究的结果进行比较是可行的 新西兰和法罗群岛的暴露婴儿。使用的人口 在纵向研究中提出了汞水平的广泛范围，因此 这一结果可用于评估美国的健康风险。 由于食用鱼类中的甲基汞而导致的种群数量减少。

DESCRIPTION: The main objective of the application is to better define the human health risks associated with prenatal and early postnatal exposure to methylmercury in fish. Subtle psychological and behavioral changes will be measured and related to the exposure of mothers during pregnancy. The study will be conducted on a cohort of 740 children from a population in the Seychelles Islands, whose diet consists primarily of large amounts of ocean fish. The application will extend the evaluation of developmental toxicity of methylmercury on the cohort to include the age of 7-8 years, which will make it feasible to compare results with those from studies of prenatally exposed infants in New Zealand and the Faeroe Islands. The population used in the longitudinal study presents a wide range in mercury levels so that the results can be applied in assessing the health risks in the U.S. population due to consumption of methylmercury in fish.