PROJECT TOWARDS NO DRUG ABUSE COMPONENTS ANALYSIS

描述：(申请人摘要) 本提案是对RFA 00-004《下一代药物滥用》的回应 我们建议研究两者的相对重要性。 无毒校本工程的理论内容构成 滥用(TND)课程在预防烟草药物滥用方面的作用， 酒精、大麻和硬毒品使用(认知认知与行为认知 技能，而不是它们的组合)。TND项目是一个经过经验验证的 指示的药物滥用预防计划，一年来取得积极进展 三个实验性复制试验的结果。指导将会是 由经验丰富的项目工作人员、健康教育者和学校提供 教师最近接受了该计划的培训，作为考核实施者的一种手段 特点。计划内容和实施者的影响 将在两个不同的青年队列中检查特征 在随机实验设计中，根据上下文定义的风险。项目和 学校教职员工授课计划将在12所高中实施 与4所标准护理(对照)条件学校相比， 在两个学校背景下重复的七条件随机设计 (传统高中和非传统高中，共32所学校)。我们将评估 学生吸毒行为基线(前测)、后计划(即刻 测试后)，并进行1年的随访期。我们将应用一系列复杂的 对收集的数据进行分析的模型，用于潜在的实验、调解 以及由假设所指定的调节效应，这些假设由 潜在的理论基础。

DESCRIPTION: (Applicant's Abstract) This proposal is a response to RFA 00-004, "The Next Generation of Drug Abuse Prevention Research." We propose to examine the relative importance of the two theoretical content components of the school-based Project Towards No Drug Abuse (TND) curricula in effecting drug abuse prevention effects on tobacco, alcohol, marijuana and hard drug use (cognitive perception versus behavioral skills, versus their combination). Project TND is an empirically validated indicated drug abuse prevention program, which has shown positive one-year outcomes over three experimental replication trials. Instruction will be provided by both experienced project staff health educators and school teachers recently trained in the program as a means of examining implementer characteristics. The impact of the program content and implementer characteristics will be examined in two cohorts of youth varying in contextually defined risk, in a randomized experimental design. Project and school staff-delivered classroom programs will be implemented in 12 high schools and compared to 4 standard care (control) condition schools, in a seven-condition randomized design replicated across two school contexts (traditional and alternative high schools, 32 schools total). We will assess student drug use behavior at baseline (pretest), post program (immediate post-test), and 1-year follow-up. We will apply a series of sophisticated models to analyze the collected data for potential experimental, mediational and moderational effects as specified by hypotheses generated from the underlying theoretical base.