CORE--INTERVENTION

干预核心的总体目标是推进护理干预的科学，以预防或管理脆弱人群中的慢性病。随着慢性病的流行，开发和测试护理干预措施以预防和管理慢性病变得越来越重要。有大量的描述性文献在描述患有慢性病是什么样子，然而，大量的工作在那个阶段萎靡不振，从来没有转移到干预措施的发展。干预核心的具体目标是：1)促进调查人员从描述性研究转向干预措施的开发和测试；2)通过检查选定结果的中介因素，探索干预措施的作用机制；3)通过探索治疗效果的调节因素，特别强调脆弱性指标作为潜在调节因素的作用，帮助调查人员评估测试的干预措施的不同效力；4)通过确定最适用的背景和问题，探索量身定制的干预措施的使用；以及5)增进成本分析技术的知识，并在干预研究中更多地使用成本效益和成本效益分析。干预核心将采用以下战略来实现其目标：关于问题识别和干预设计的协商；关于分析干预效果的调解人和调解人的统计技术的协商；关于成本分析的协商；研讨会和座谈会；以及为该区域其他机构的研究人员设计干预措施的继续教育方案。

The Intervention Core's overall goal is to advance the science on nursing interventions to prevent or manage chronic illness in vulnerable populations. With the prevalence of chronic illness, it becomes increasingly important to develop and test nursing interventions to prevent and manage chronic illness. There is a substantial body of descriptive literature 'Dn what it is like to live with a chronic illness, however, a great deal of the work languishes at that stage and never moves to the development of interventions. The Specific Aims of the Intervention Core are to 1) facilitate movement of investigators from descriptive research to the development and testing of interventions, 2) explore the mechanisms of action of interventions by examining the mediators of selected outcomes, 3) help investigators evaluate the differential effectiveness of tested interventions by exploring moderators of treatment effect, with particular emphasis on the role of indicators of vulnerabilities as potential moderators, 4) explore the use of tailored interventions by identifying the contexts and problems for which they are most applicable, and 5) advance knowledge of cost analysis techniques and increase the use of cost benefit and cost effectiveness analyses in intervention studies. The Intervention Core will employ the following strategies to achieve its aims: consultation on problem identification and intervention design; consultation on statistical techniques for the analysis of mediators and moderators of intervention effects; consultation on cost analysis; seminars and colloquia; and continuing education programs on designing interventions for researchers in other institutions throughout the region.