PURCHASE OF A HIGH SENSITIVITY PROTEIN SEQUENCER

购买高灵敏度蛋白质测序仪

• 批准号: 2487488
• 负责人: W Todd MILLER
• 金额: $ 13.28万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-03-18 至 1999-03-17
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2487488
• 关键词: biomedical equipment purchase; protein sequence

Funds are requested for the acquisition of a high sensitivity, rapid throughput protein sequencer for the sequence analysis of proteins and peptides. The instrument will be housed in the Center for the Analysis and Synthesis of Macromolecules (CASM) in the Department of Physiology & Biophysics at Stony Brook, and operated as a shared facility overseen by the School of Medicine and the Center for Biotechnology. Projects will be conducted by eight major faculty, and as many as twenty other faculty users from the departments of Physiology & Biophysics, Medicine, Biochemistry, Chemistry, Oral Biology & Pathology, and other departments whose research requires the sequence analysis of proteins and peptides. Samples to be analyzed include covalent protein-ligand complexes, glycopeptides, phosphopeptides, photoaffinity modified peptides, and peptides from enzymatic digests of posttranslationally-modified proteins.

所需资金用于收购敏感度高、速度快 用于蛋白质和蛋白质序列分析的吞吐量蛋白质测序仪 多肽。仪器将被安置在分析中心 和大分子合成(CASM)在生理学和医学部 石溪生物物理学，并作为一个共享设施运营，由 医学院和生物技术中心。项目将 由8名主要教员和多达20名其他教员主持 生理生物物理系、医学系、医学系、 生物化学、化学、口腔生物与病理等系 他们的研究需要蛋白质和多肽的序列分析。 待分析的样品包括共价蛋白质-配体复合体， 糖肽、磷酸肽、光亲和修饰多肽以及 来自翻译后修饰蛋白质的酶消化的多肽。