SARS-CoV-2 infection, transmission dynamics and household impact in Malawi (SCATHIM)

马拉维的 SARS-CoV-2 感染、传播动态和家庭影响 (SCATHIM)

• 批准号: MR/V02860X/1
• 负责人: Victor Mwapasa
• 金额: $ 89.84万
• 依托单位: University of Malawi
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MR%2FV02860X%2F1
• 关键词: SARS; CoV; infection; transmission; dynamics

Sub-Saharan African countries have adopted COVID-19 prevention methods similar to those used in developed countries although their people live in a different context. The spread of COVID-19 in African households and people's adherence to preventive measures are not known, but this information is required to develop appropriate prevention measures. We aim to determine the intensity of COVID-19 spread in households located in urban medium-density, urban high-density and rural-high density areas in Malawi, Africa, factors that promote the spread of the disease and the impact of the disease on people's lives. Our specific objectives are to: (1) estimate the proportion of people living in the same household with infected people who become infected, (2) assess whether the risk of getting infected and developing severe symptoms are influenced by personal and nutritional characteristics and immunity to COVID-19; other infections (HIV, TB, malaria) or their treatments; and the household environment (3) assess whether the use of personal protective equipment is acceptable, feasible, and effective among people living with infected individuals (4) describe the experiences of caregivers of COVID-19 infected individuals (5) estimate the costs and lost income associated with home-based care for infected people. Study findings will help to identify high risk households/areas and design appropriate social safety nets for affected households. Our research team's existing collaboration with policy makers and local health department will facilitate the use of research findings to strengthen the fight against the disease.

撒哈拉以南非洲国家采用了与发达国家类似的COVID-19预防方法，尽管其人民生活在不同的环境中。目前尚不清楚COVID-19在非洲家庭中的传播情况以及人们对预防措施的遵守情况，但需要这些信息来制定适当的预防措施。我们的目标是确定位于非洲马拉维城市中密度、城市高密度和农村高密度地区的家庭中COVID-19传播的强度、促进疾病传播的因素以及疾病对人们生活的影响。我们的具体目标是：（1）估计与感染者生活在同一家庭中的人感染的比例，（2）评估感染和出现严重症状的风险是否受到个人和营养特征以及对COVID-19的免疫力的影响;其他感染（艾滋病毒、结核病、疟疾）或其治疗;和家庭环境（3）评估个人防护设备的使用是否可接受、可行（4）描述COVID-19感染者的护理人员的经历（5）估计与感染者的家庭护理相关的成本和收入损失。研究结果将有助于确定高风险家庭/地区，并为受影响家庭设计适当的社会安全网。我们的研究团队目前与政策制定者和当地卫生部门的合作将有助于利用研究成果加强对抗疾病。

项目成果

Household costs and care seeking patterns associated with COVID-19 in Blantyre, Malawi.

• DOI: 10.1371/journal.pgph.0002003
• 发表时间: 2023
• 期刊: PLOS global public health

"Why take the patient back home?": Exploring the lived experiences of caregivers of COVID-19-infected individuals in Blantyre, Malawi.

• DOI: 10.1371/journal.pgph.0001601
• 发表时间: 2023
• 期刊: PLOS global public health