Development of novel anti-malaria drugs that block parasite invasion

疟疾是一种毁灭性的寄生虫病，每年导致40多万人死亡。抗疟疾药物在帮助根除疟疾方面发挥了关键作用，但令人极为关切的是，寄生虫正在对现有药物产生抗药性。我们正在开发药物，以防止寄生虫在人类血液中入侵和扩散，从而导致疟疾。我们还在发现这些药物是如何发挥作用的，目的是极大地改善它们在临床应用方面的表现。

Malaria is a devastating parasitic disease that kills over 400,000 people a year. Antimalarial drugs play a crucial role in helping eradicate malaria but of great concern is that parasites are becoming resistant to current drugs. We are developing drugs that prevent parasites from invading and proliferating in human blood which causes malaria. We are also discovering how the drugs work with the aim of greatly improving their performance towards clinical uptake.