Development of novel anti-malaria drugs that block parasite invasion

开发阻止寄生虫入侵的新型抗疟疾药物

• 批准号: nhmrc : 2001073
• 金额: $ 103.56万
• 依托单位国家: 澳大利亚
• 项目类别: Ideas Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/development-novel-anti-parasite-invasion/1779693
• 关键词: Development; novel; anti; malaria; drugs

Malaria is a devastating parasitic disease that kills over 400,000 people a year. Antimalarial drugs play a crucial role in helping eradicate malaria but of great concern is that parasites are becoming resistant to current drugs. We are developing drugs that prevent parasites from invading and proliferating in human blood which causes malaria. We are also discovering how the drugs work with the aim of greatly improving their performance towards clinical uptake.

疟疾是一种毁灭性的寄生虫病，每年造成40多万人死亡。抗疟疾药物在帮助根除疟疾方面发挥着至关重要的作用，但令人非常担忧的是，寄生虫正在对目前的药物产生抗药性。我们正在开发药物，以防止寄生虫入侵并在人体血液中增殖，从而导致疟疾。我们还发现了这些药物是如何工作的，目的是大大提高它们在临床应用中的表现。