FAMILY STUDY OF INHERITENCE OF P450IIIA4 GENE DEFECT

P450IIIA4基因缺陷遗传的家系研究

• 批准号: 6297169
• 负责人: D K TURGEON
• 金额: $ 0.02万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6297169
• 关键词: clinical research; cytochrome P450; family genetics; gene expression; genetic disorder; genetic regulation; human subject

This is a pilot study to evaluate the genomic DNA of 5 children of patient BG for possible inheritance of a defect in the 5' regulatory region of the P450IIIA4 gene. The study will determine if it is resasonable to proceed with an in depth investigation of BG's children and children.

这是一项先导性研究，旨在评估患者BG的5个孩子的基因组DNA是否可能遗传了P450IIIA4基因5‘调控区的缺陷。这项研究将确定是否有理由继续对BG的孩子和儿童进行深入调查。